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Line 665: |
Line 665: |
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| ==Adamantinoma== | | ==Adamantinoma== |
| :Should '''not''' be confused with ''[[adenomatoid tumour]]''.
| | {{Main|Adamantinoma}} |
| ===General===
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| Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref>
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| *Rare: < 1% of bone tumours.
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| *25-35 years old.
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| *Tibia, fibula.
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| *Benign, may be locally aggressive.
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| *Cousin of [[ameloblastoma]]. (???)
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| | |
| ===Radiology===
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| *Intracortical, radiolucent.
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| ===Microscopic===
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| Features:
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| *Biphasic tumour:
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| *#Fibrous/spindle cell component.
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| *#Epithelial component.
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| DDx:<ref name=pathcon_adam>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2]. Accessed on: 28 April 2011.</ref>
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| *Vascular tumours ([[Epithelioid hemangioendothelioma]]).
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| *Metastatic carcinoma.
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| ====Images====
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| <gallery>
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| Image:Adamantinoma_-_intermed_mag.jpg | Adamantinoma - intermed. mag. (WC)
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| </gallery>
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| www:
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| *[http://southbaypath.org/CaseImages/sb5260/AdamantinomaBiopsy3.jpg Adamantinoma (southbaypath.org)].<ref>URL: [http://southbaypath.org/CaseImages/sb5260/sb5260.htm http://southbaypath.org/CaseImages/sb5260/sb5260.htm]. Accessed on: 7 December 2010.</ref>
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| | |
| ===IHC===
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| Features:<ref name=pathcon_adam/>
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| *CK14 +ve (HMWK).<ref>URL: [http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]. Accessed on: 28 April 2011.</ref>
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| *CK19 +ve (LMWK).
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| *CK8/18 -ve (LMWK).
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| ==Brown tumour== | | ==Brown tumour== |