Difference between revisions of "Osteoblastoma"

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#redirect [[Chondro-osseous tumours#Osteoblastoma]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Osteoblastoma_-_low_mag.jpg
| Width      =
| Caption    = Osteoblastoma. [[H&E stain]].
| Micro      = anastomosing bony [[trabeculae]] with variable mineralization, osteoblast rimming, no nuclear atypia of osteocytes
| Subtypes  =
| LMDDx      = [[osteoid osteoma]], [[osteosarcoma]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      =
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      = > 1.5 cm (smaller lesions [[osteoid osteoma]])
| Endoscopy  =
| Prognosis  =
| Other      =
| ClinDDx    = [[osteosarcoma]]
}}
'''Osteoblastoma''' is benign primary [[bone tumour]].


==General==
*Benign bone tumour.
*Uncommon.<ref name=pmid23362588>{{Cite journal  | last1 = Khan | first1 = IS. | last2 = Thakur | first2 = JD. | last3 = Chittiboina | first3 = P. | last4 = Nanda | first4 = A. | title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. | journal = J La State Med Soc | volume = 164 | issue = 5 | pages = 251-5 | month =  | year =  | doi =  | PMID = 23362588 }}</ref>
==Gross==
*Bone.
**May be in the spine.<ref>{{Cite journal  | last1 = Boriani | first1 = S. | last2 = Amendola | first2 = L. | last3 = Bandiera | first3 = S. | last4 = Simoes | first4 = CE. | last5 = Alberghini | first5 = M. | last6 = Di Fiore | first6 = M. | last7 = Gasbarrini | first7 = A. | title = Staging and treatment of osteoblastoma in the mobile spine: a review of 51 cases. | journal = Eur Spine J | volume = 21 | issue = 10 | pages = 2003-10 | month = Oct | year = 2012 | doi = 10.1007/s00586-012-2395-8 | PMID = 22695702 }}</ref>
*'''Must''' be greater 1.5 cm by definition.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref>
==Microscopic==
Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref>
*Anastomosing bony [[trabeculae]] with:
**Osteoblasts rimming.
***Cells line-up at edge of bone.
Notes:
*Histomorphologically near identical/indistinguishable from ''[[osteoid osteoma]]''.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref>
===Images===
<gallery>
Image:Osteoblastoma_-_high_mag.jpg | Osteoblastoma - high mag. (WC)
Image:Osteoblastoma_-_low_mag.jpg | Osteoblastoma - low mag. (WC)
</gallery>
==Sign out==
<pre>
BONE, LEFT FEMUR, EXCISION:
- OSTEOBLASTOMA.
</pre>
==See also==
*[[Chondro-osseous tumours]].
*[[Bone]].
==References==
{{Reflist|2}}
[[Category:Chondro-osseous tumours]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]
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