Difference between revisions of "Medical liver disease"

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*+/-''Chicken-wire'' perisinusoidal fibrosis +/- zone III (centrilobular) fibrosis (early).
*+/-''Chicken-wire'' perisinusoidal fibrosis +/- zone III (centrilobular) fibrosis (early).
**Late-stage disease - portal bridging.<ref name=pmid14991537>{{Cite journal  | last1 = Gramlich | first1 = T. | last2 = Kleiner | first2 = DE. | last3 = McCullough | first3 = AJ. | last4 = Matteoni | first4 = CA. | last5 = Boparai | first5 = N. | last6 = Younossi | first6 = ZM. | title = Pathologic features associated with fibrosis in nonalcoholic fatty liver disease. | journal = Hum Pathol | volume = 35 | issue = 2 | pages = 196-9 | month = Feb | year = 2004 | doi =  | PMID = 14991537 }}</ref>
**Late-stage disease - portal bridging.<ref name=pmid14991537>{{Cite journal  | last1 = Gramlich | first1 = T. | last2 = Kleiner | first2 = DE. | last3 = McCullough | first3 = AJ. | last4 = Matteoni | first4 = CA. | last5 = Boparai | first5 = N. | last6 = Younossi | first6 = ZM. | title = Pathologic features associated with fibrosis in nonalcoholic fatty liver disease. | journal = Hum Pathol | volume = 35 | issue = 2 | pages = 196-9 | month = Feb | year = 2004 | doi =  | PMID = 14991537 }}</ref>
Image: [http://commons.wikimedia.org/wiki/File:Steatohepatitis_high_mag.jpg Steatohepatitis (WC)].


DDx:
DDx:
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*[[Drug-induced liver disease]].
*[[Drug-induced liver disease]].


====Image====
<gallery>
Image:Steatohepatitis_high_mag.jpg | Steatohepatitis. (WC)
</gallery>
===Grading steatohepatitis===
===Grading steatohepatitis===
Grading inflammation:<ref name=pmid10484010>Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Am J Gastroenterol. 1999 Sep;94(9):2467-74. PMID 10484010.</ref>
Grading inflammation:<ref name=pmid10484010>Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Am J Gastroenterol. 1999 Sep;94(9):2467-74. PMID 10484010.</ref>
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