Difference between revisions of "Phosphaturic mesenchymal tumour"

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Phosphaturic mesenchymal tumour (view source)

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{{ Infobox diagnosis
#redirect [[Phosphaturic mesenchymal tumour, mixed connective tissue type]]
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'''Phosphaturic mesenchymal tumor''' is a rare tumour.
 
One type is the '''phosphaturic mesenchymal tumour, mixed connective tissue type''', abbreviated '''PMTMCT'''.
 
==General==
*Extremely rare.
*Hypophosphatemia.<ref name=pmid23722193>{{Cite journal  | last1 = Papierska | first1 = L. | last2 = Ćwikła | first2 = JB. | last3 = Misiorowski | first3 = W. | last4 = Rabijewski | first4 = M. | last5 = Sikora | first5 = K. | last6 = Wanyura | first6 = H. | title = Unusual case of phosphaturic mesenchymal tumor. | journal = Pol Arch Med Wewn | volume = 123 | issue = 5 | pages = 255-6 | month =  | year = 2013 | doi =  | PMID = 23722193 }}</ref>
*Most common cause of ''oncogenic osteomalacia'' (tumour-induced osteomalacia).<ref name=pmid22927293>{{Cite journal  | last1 = William | first1 = J. | last2 = Laskin | first2 = W. | last3 = Nayar | first3 = R. | last4 = De Frias | first4 = D. | title = Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology. | journal = Diagn Cytopathol | volume = 40 Suppl 2 | issue =  | pages = E109-13 | month = Aug | year = 2012 | doi = 10.1002/dc.21647 | PMID = 22927293 }}</ref>
 
==Gross==
*Soft tissue ''or'' [[bone]].<ref name=pmid22532501>{{Cite journal  | last1 = Jiang | first1 = Y. | last2 = Xia | first2 = WB. | last3 = Xing | first3 = XP. | last4 = Silva | first4 = BC. | last5 = Li | first5 = M. | last6 = Wang | first6 = O. | last7 = Zhang | first7 = HB. | last8 = Li | first8 = F. | last9 = Jing | first9 = HL. | title = Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. | journal = J Bone Miner Res | volume = 27 | issue = 9 | pages = 1967-75 | month = Sep | year = 2012 | doi = 10.1002/jbmr.1642 | PMID = 22532501 }}</ref>
*Often small - thus hard to identify.<ref name=pmid23868423>{{Cite journal  | last1 = Ledford | first1 = CK. | last2 = Zelenski | first2 = NA. | last3 = Cardona | first3 = DM. | last4 = Brigman | first4 = BE. | last5 = Eward | first5 = WC. | title = The Phosphaturic Mesenchymal Tumor: Why is Definitive Diagnosis and Curative Surgery Often Delayed? | journal = Clin Orthop Relat Res | volume =  | issue =  | pages =  | month = Jul | year = 2013 | doi = 10.1007/s11999-013-3178-1 | PMID = 23868423 }}</ref>
 
==Microscopic==
Features:<ref name=pmid22927293/>
*Spindle cells without atypia in an eosinophilic matrix.
*Osteoclast-type [[giant cell]]s.
*+/-Calcifications.
 
Image:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783479/figure/F4/ PMTMCT (nih.gov)].<ref name=pmid19828339>{{Cite journal  | last1 = Woo | first1 = VL. | last2 = Landesberg | first2 = R. | last3 = Imel | first3 = EA. | last4 = Singer | first4 = SR. | last5 = Folpe | first5 = AL. | last6 = Econs | first6 = MJ. | last7 = Kim | first7 = T. | last8 = Harik | first8 = LR. | last9 = Jacobs | first9 = TP. | title = Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature. | journal = Oral Surg Oral Med Oral Pathol Oral Radiol Endod | volume = 108 | issue = 6 | pages = 925-32 | month = Dec | year = 2009 | doi = 10.1016/j.tripleo.2009.07.005 | PMID = 19828339 }}</ref>
 
==References==
{{Reflist|2}}
 
[[Category:Weird stuff]]
[[Category:Diagnosis]]
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