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Gastric antral vascular ectasia (view source)
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'''Gastric antral vascular ectasia''', abbreviated '''GAVE''', is an uncommon pathology of the [[stomach]]. It is also known as '''watermelon stomach''' due to characteristic endoscopic appearance.<ref name=pmid18625989>{{cite journal |author=Chatterjee S |title=Watermelon stomach |journal=CMAJ |volume=179 |issue=2 |pages=162 |year=2008 |month=July |pmid=18625989 |pmc=2443230 |doi=10.1503/cmaj.080461 |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18625989}}</ref> | |||
==General== | |||
*Lesion of the antrum - due to dilated capillaries. | |||
==Gross/endoscopic appearance== | |||
* Linear red streaks in antrum - oriented toward the pyloric valve... vaguely resembles a watermelon. | |||
Endoscopic images: | |||
*[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2443230&rendertype=figure&id=f1-19 Watermelon stomach (pubmedcentral.nih.gov)]. | |||
*[http://en.wikipedia.org/wiki/File:Gave.png GAVE (WP)]. | |||
==Microscopic== | |||
Features:<ref name=Ref_GLP118>{{Ref GLP|118}}</ref> | |||
*Fibrin thrombi - '''characteristic feature'''. | |||
*Dilated capillaries in lamina propria. | |||
*+/-Foveollar hyperplasia.<ref name=Ref_GLP119>{{Ref GLP|119}}</ref> | |||
DDx: | |||
*[[Portal hypertensive gastropathy]] - predominantly in the gastric body, usu. associated with [[cirrhosis]], do not have fibrin thrombi.<ref name=Ref_GLP120-1>{{Ref GLP|120-1}}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Gastric_antral_vascular_ectasia_-_2_-_intermed_mag.jpg | GAVE - intermed. mag. (WC) | |||
Image:Gastric_antral_vascular_ectasia_-_2_-_very_high_mag.jpg | GAVE - very high mag. (WC) | |||
Image:Gastric_antral_vascular_ectasia_-_very_high_mag.jpg | GAVE - two thrombi - very high mag. (WC) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
STOMACH, BIOPSY: | |||
- GASTRIC ANTRAL VASCULAR ECTASIA WITH FOVEOLAR HYPERPLASIA. | |||
- MILD CHRONIC ACTIVE ANTRAL GASTRITIS. | |||
- NEGATIVE FOR INTESTINAL METAPLASIA. | |||
- NEGATIVE FOR DYSPLASIA. | |||
- NEGATIVE FOR HELICOBACTER ORGANISMS. | |||
</pre> | |||
===Micro=== | |||
The sections show antral-type gastric mucosa with dilated lamina propria blood vessels and intravascular fibrin thrombi. There is mild foveolar hyperplasia. Numerous neutrophils are present between the foveollar cells and within the lamina propria. Several large clusters of plasma cells are present in the lamina propria. | |||
==See also== | |||
*[[Stomach]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Stomach]] | |||
[[Category:Gastrointestinal pathology]] | |||