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| VAS DEFERENS, RIGHT AND LEFT, VASECTOMY: | | VAS DEFERENS, RIGHT AND LEFT, VASECTOMY: |
| - VAS DEFERENS WITHIN NORMAL LIMITS, LOOPS OF EPITHELIUM AND MUSCLE LAYERS PRESENT. | | - VAS DEFERENS WITHIN NORMAL LIMITS, LOOPS OF EPITHELIUM AND MUSCLE LAYERS PRESENT. |
| | </pre> |
| | |
| | =====Alternate===== |
| | <pre> |
| | VAS DEFERENS, RIGHT AND LEFT, VASECTOMY: |
| | - VAS DEFERENS WITHIN NORMAL LIMITS, LOOPS OF EPITHELIUM AND MUSCLE LAYERS PRESENT |
| | ON BOTH SLIDE A1-1 AND SLIDE A2-1. |
| | </pre> |
| | |
| | =====One container is empty===== |
| | <pre> |
| | A. VAS DEFERENS ("LEFT"), VASECTOMY: |
| | - VAS DEFERENS WITHIN NORMAL LIMITS, LOOPS OF EPITHELIUM AND MUSCLE LAYERS PRESENT |
| | ON BOTH SLIDE A1-1 AND SLIDE A2-1. |
| | - SEE COMMENT. |
| | |
| | B. VAS DEFERENS ("RIGHT"), VASECTOMY: |
| | - NO TISSUE IDENTIFIED, SEE COMMENT. |
| | |
| | COMMENT: |
| | Both specimens (left vas deferens and right vas deferens) may have been placed in |
| | container A. See 'gross' section of report. Clinical correlation is essential. |
| </pre> | | </pre> |
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| *#It is possible that a section with a loop of epithelium is the result of a non-transecting cut that generates an ovoid defect in the wall of the vas deferens. | | *#It is possible that a section with a loop of epithelium is the result of a non-transecting cut that generates an ovoid defect in the wall of the vas deferens. |
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| ==Vasitis nodosa== | | ====No definite epithelium==== |
| ===General=== | | <pre> |
| *Classically develops post-vasovasostomy ([[vasectomy]] reversal).<ref name=pmid3366928>{{Cite journal | last1 = Hirschowitz | first1 = L. | last2 = Rode | first2 = J. | last3 = Guillebaud | first3 = J. | last4 = Bounds | first4 = W. | last5 = Moss | first5 = E. | title = Vasitis nodosa and associated clinical findings. | journal = J Clin Pathol | volume = 41 | issue = 4 | pages = 419-23 | month = Apr | year = 1988 | doi = | PMID = 3366928 | PMC=1141468 }}</ref>
| | A. VAS DEFERENS, LEFT, VASECTOMY: |
| **Seen in association with other surgical procedures.
| | - VAS DEFERENS WITHIN NORMAL LIMITS, LOOP OF EPITHELIUM AND MUSCLE LAYERS PRESENT. |
| **May be seen in the context of infertility (without prior vasectomy).
| |
| *Some similarity to [[salpingitis isthmica nodosa]].<ref name=pmid3366928/>
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| ===Gross===
| | B. VAS DEFERENS, RIGHT, VASECTOMY: |
| *Mass.
| | - COMPATIBLE WITH VAS DEFERENS, WITHOUT COMPLETE LOOP OF EPITHELIUM, SEE COMMENT. |
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| ===Microscopic===
| | COMMENT - PART B: |
| Features:<ref name=pmid3366928/>
| | Definite vas deferens epithelium is not identified; however, the muscle layering seen is |
| *Tubules in wall of vas deferens.
| | compatible with a vas deferens. Levels were cut (x4). |
| **Lined by columnar/cuboidal epithelium.
| |
| ***May have mitotic activity.
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| ***Nucleoli.
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| ***Contain sperm - small, dark staining, teardrop-shaped (~1 micrometer) - '''key feature'''.
| |
| ****The tail is rarely seen completely in the plane of section.
| |
| *+/-[[Sperm granuloma]]s.
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| **Histocytes - abundant foamy cytoplasm.
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| **Sperm - small, dark staining, teardrop-shaped (~1 micrometer).
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| DDx:
| | Clinical correlation is suggested. |
| *[[Metastatic]] carcinoma, especially [[prostate carcinoma]].
| | </pre> |
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| Notes:
| | ====No vas deferens identified==== |
| *Can be confused with [[prostatic adenocarcinoma]]:<ref name=pmid3984936>{{Cite journal | last1 = Balogh | first1 = K. | last2 = Travis | first2 = WD. | title = Benign vascular invasion in vasitis nodosa. | journal = Am J Clin Pathol | volume = 83 | issue = 4 | pages = 426-30 | month = Apr | year = 1985 | doi = | PMID = 3984936 }}</ref>
| | <pre> |
| **May "invade" vascular spaces - associated with elastosis (breakdown of elastic fibres<ref>URL: [http://medical-dictionary.thefreedictionary.com/elastosis http://medical-dictionary.thefreedictionary.com/elastosis]. Accessed on: 26 September 2011.</ref>).
| | A. CONNECTIVE TISSUE, RIGHT, "VASECTOMY": |
| | - NO VAS DEFERENS IDENTIFIED. |
| | - BENIGN FIBROMUSCULAR TISSUE WITH INTERMEDIATE BLOOD VESSELS. |
|
| |
|
| ====Image====
| | B. CONNECTIVE TISSUE, LEFT, "VASECTOMY": |
| <gallery>
| | - NO VAS DEFERENS IDENTIFIED. |
| Image: Vasitis nodosa -11- intermed mag.jpg | VN - intermed. mag. (WC)
| | - BENIGN FIBROMUSCULAR TISSUE WITH INTERMEDIATE BLOOD VESSELS. |
| Image: Vasitis nodosa -12- intermed mag.jpg | VN - intermed. mag. (WC)
| |
| Image: Vasitis nodosa -11- high mag.jpg | VN - high mag. (WC)
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| Image: Vasitis nodosa -12- high mag.jpg | VN - high mag. (WC)
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| Image: Vasitis nodosa -11- very high mag.jpg | VN - very high mag. (WC)
| |
| </gallery>
| |
| <gallery>
| |
| Image: Vasitis nodosa -21- high mag.jpg | VN - high mag. (WC)
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| Image: Vasitis nodosa -21- very high mag.jpg | VN - Very high mag. (WC)
| |
| </gallery>
| |
| www:
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| *[http://www.webpathology.com/image.asp?n=11&Case=40 Vasitis nodosa (webpathology.com)].
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| ===IHC===
| | COMMENT: |
| *PSA -ve.
| | Levels were cut (x3). Clinical correlation is suggested. |
| *PSAP -ve.
| | </pre> |
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| ===Sign out=== | | ==Vasitis nodosa== |
| <pre>
| | {{Main|Vasitis nodosa}} |
| A. VAS DEFERENS WITH GRANULOMA, RIGHT, VASOVASOSTOMY:
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| - VASITIS NODOSA AND SPERM GRANULOMAS.
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| - COMPLETE CROSS SECTION OF VAS DEFERENS.
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| | |
| B. VAS DEFERENS WITH GRANULOMA, LEFT, VASOVASOSTOMY:
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| - VASITIS NODOSA AND SPERM GRANULOMAS.
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| - COMPLETE CROSS SECTION OF VAS DEFERENS.
| |
| </pre>
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| ==Bilateral absence of the vas deferens== | | ==Bilateral absence of the vas deferens== |
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| *[[Prostate gland]]. | | *[[Prostate gland]]. |
| *[[Testis]]. | | *[[Testis]]. |
| | *[[Male infertility]]. |
| | *[[Epididymis]]. |
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| ==References== | | ==References== |