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==Worms & stuff== | ==Worms & stuff== | ||
==Toxoplasma== | |||
===General=== | |||
*Common CNS infection. | |||
===Microscopic=== | |||
General: | |||
*Dependent on location in body. | |||
Lymph node - features:<ref name=Ref_ILNP113>{{Ref ILNP|113}}</ref> | |||
*Reactive germinal centers (pale areas - larger than usual). | |||
**Often poorly demarcated - due to loose epithelioid cell clusters at germinal center edge - '''key feature'''. | |||
*Epithelioid cells - perifollicular & intrafollicular. | |||
**Loose aggregates of histiocytes (do not form round granulomas): | |||
***Abundant pale cytoplasm. | |||
***Nucleoli. | |||
*Monocytoid cells (monocyte-like cells) - in cortex & paracortex. | |||
**Large cells in islands/sheets '''key feature''' with: | |||
***Abundant pale cytoplasm - '''important'''. | |||
***Well-defined cell border - '''important'''. | |||
***Singular nucleus. | |||
**Cell clusters usually have interspersed neutrophils. | |||
Images (lymph node): | |||
*[http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-_low_mag.jpg Toxoplasmosis - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-_high_mag.jpg Toxoplasmosis - high mag. (WC)]. | |||
Image (CNS): | |||
*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/N0I001-PQ01-M.htm CNS toxoplasmosis]. | |||
==Strongyloides== | ==Strongyloides== |
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