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Difference between revisions of "Endosalpingiosis"
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# | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Endosalpingiosis_-_high_mag.jpg | |||
| Width = | |||
| Caption = Endosalpingiosis. [[H&E stain]]. | |||
| Micro = cystic lesion with ciliated epithelium surrounded by fibrous stroma, [[psammoma bodies]] | |||
| Subtypes = | |||
| LMDDx = [[endometriosis]], [[serous carcinoma]], papillary carcinoma, [[peritoneal inclusion cyst]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = may be associated with endometriosis; incidental finding | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Endosalpingiosis''' is a benign entity that can be confused for [[cancer]]. | |||
==General== | |||
*Benign entity that may lead to a misdiagnosis of adenocarcinoma<ref name=pmid19415948>{{cite journal |author=Lin O |title=Challenges in the interpretation of peritoneal cytologic specimens |journal=Arch. Pathol. Lab. Med. |volume=133 |issue=5 |pages=739–42 |year=2009 |month=May |pmid=19415948 |doi= |url=}}</ref> or serous carcinoma. | |||
*The clinical significance of endosalpingiosis is not definitively settled; opinions differ on whether it is: | |||
*# associated with pelvic pain,<ref name=pmid9350013>{{Cite journal | last1 = deHoop | first1 = TA. | last2 = Mira | first2 = J. | last3 = Thomas | first3 = MA. | title = Endosalpingiosis and chronic pelvic pain. | journal = J Reprod Med | volume = 42 | issue = 10 | pages = 613-6 | month = Oct | year = 1997 | doi = | PMID = 9350013 }}</ref> ''or'' | |||
*# an incidental finding discovered in the course of investigating something else (pelvic pain, menstrual irregularities, infertility).<ref name=pmid12039470>{{Cite journal | last1 = Heinig | first1 = J. | last2 = Gottschalk | first2 = I. | last3 = Cirkel | first3 = U. | last4 = Diallo | first4 = R. | title = Endosalpingiosis-an underestimated cause of chronic pelvic pain or an accidental finding? A retrospective study of 16 cases. | journal = Eur J Obstet Gynecol Reprod Biol | volume = 103 | issue = 1 | pages = 75-8 | month = Jun | year = 2002 | doi = | PMID = 12039470 }}</ref> | |||
==Microscopic== | |||
Features:<ref>URL: [http://radiographics.rsna.org/content/29/2/347.full http://radiographics.rsna.org/content/29/2/347.full]. Accessed on: 27 May 2010.</ref> | |||
*Cystic lesions with: | |||
**Ciliated (tubal type) epithelium, without endometrial stroma. | |||
***Endosalpingiosis is surrounded by fibrous stroma; tubal type epithelial surrounded by ovarian stroma is a variant of [[endometriosis]]. | |||
*Associated with [[psammoma bodies]].<ref name=pmid1774734>{{cite journal |author=Hallman KB, Nahhas WA, Connelly PJ |title=Endosalpingiosis as a source of psammoma bodies in a Papanicolaou smear. A case report |journal=J Reprod Med |volume=36 |issue=9 |pages=675–8 |year=1991 |month=September |pmid=1774734 |doi= |url=}}</ref> | |||
DDx:<ref>{{Cite journal | last1 = Rosenberg | first1 = P. | last2 = Nappi | first2 = L. | last3 = Santoro | first3 = A. | last4 = Bufo | first4 = P. | last5 = Greco | first5 = P. | title = Pelvic mass-like florid cystic endosalpingiosis of the uterus: a case report and a review of literature. | journal = Arch Gynecol Obstet | volume = 283 | issue = 3 | pages = 519-23 | month = Mar | year = 2011 | doi = 10.1007/s00404-010-1700-1 | PMID = 20931212 }}</ref> | |||
*Serous carcinoma. | |||
*[[Peritoneal inclusion cyst]]. | |||
Notes: | |||
#Not associated with hemorrhage.<ref>URL: [http://radiographics.rsna.org/content/29/2/347.full http://radiographics.rsna.org/content/29/2/347.full]. Accessed on: 27 May 2010.</ref> | |||
#In a lymph node, endosalpingiosis may be misinterpreted as a [[lymph node metastasis|metastasis]]!<ref name=pmid20631604>{{Cite journal | last1 = Corben | first1 = AD. | last2 = Nehhozina | first2 = T. | last3 = Garg | first3 = K. | last4 = Vallejo | first4 = CE. | last5 = Brogi | first5 = E. | title = Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma. | journal = Am J Surg Pathol | volume = 34 | issue = 8 | pages = 1211-6 | month = Aug | year = 2010 | doi = 10.1097/PAS.0b013e3181e5e03e | PMID = 20631604 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Endosalpingiosis_-_low_mag.jpg | Endosalpingiosis - low mag. (WC/Nephron) | |||
Image:Endosalpingiosis_-_high_mag.jpg | Endosalpingiosis - high mag. (WC/Nephron) | |||
Image:Endosalpingiosis_-_cropped_2_-_very_high_mag.jpg | Endosalpingiosis - very high mag. (WC/Nephron) | |||
Image:Endosalpingiosis_in_lymph_node_-_intermed_mag.jpg | Endosalpingiosis in a LN - intermed. mag. (WC/Nephron) | |||
Image:Endosalpingiosis_in_lymph_node_-_very_high_mag.jpg | Endosalpingiosis in a LN - very high mag. (WC/Nephron) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
OVARIAN FOSSA, RIGHT, BIOPSY: | |||
- ENDOMETRIOSIS. | |||
- ENDOSALPINGIOSIS. | |||
- FIBROADIPOSE TISSUE PARTIALLY COVERED BY MESOTHELIUM. | |||
</pre> | |||
==See also== | |||
*[[Gynecologic pathology]]. | |||
*[[Endometriosis]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | |||
[[Category:Gynecologic pathology]] | |||