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Difference between revisions of "Medical liver disease"
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→Common: more
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*Zone 3 necrosis. | *Zone 3 necrosis. | ||
**Tx: N-acetylcysteine (NAC).<ref name=pmid19621836>{{cite journal |author=Millea PJ |title=N-acetylcysteine: multiple clinical applications |journal=Am Fam Physician |volume=80 |issue=3 |pages=265–9 |year=2009 |month=August |pmid=19621836 |doi= |url=}}</ref> | **Tx: N-acetylcysteine (NAC).<ref name=pmid19621836>{{cite journal |author=Millea PJ |title=N-acetylcysteine: multiple clinical applications |journal=Am Fam Physician |volume=80 |issue=3 |pages=265–9 |year=2009 |month=August |pmid=19621836 |doi= |url=}}</ref> | ||
** | ***NAC is an endogenous precursor to glutathione.<ref>URL: [http://www.mskcc.org/mskcc/html/69310.cfm http://www.mskcc.org/mskcc/html/69310.cfm]. Accessed on: 19 October 2010.</ref> | ||
**Hepatotoxicity from ''N-acetyl-p-benzoquinoneimine (NAPQI)'' due to depletion of ''glutathione''.<ref name=pmid19621836>{{cite journal |author=Millea PJ |title=N-acetylcysteine: multiple clinical applications |journal=Am Fam Physician |volume=80 |issue=3 |pages=265–9 |year=2009 |month=August |pmid=19621836 |doi= |url=}}</ref> | |||
Methotrexate - chronic use: | Methotrexate - chronic use: | ||