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| ==Warthin tumour== | | ==Warthin tumour== |
| *[[AKA]] ''papillary cystadenoma lymphomatosum''.
| | {{Main|Warthin tumour}} |
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| ===General===
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| Epidemiology:
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| *May be multicentric ~ 15% of the time.
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| *May be bilateral ~10% of the time.
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| *Classically: male > female -- changing with more women smokers.
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| *Smokers.
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| *Old - usu. 60s, very rarely < 40 years old.
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| Notes:
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| *No malignant transformation.
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| *Not in submandibular gland.
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| *Not in sublingual gland.
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| *Not in children.
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| ===Gross===
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| *Motor-oil like fluid.
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| *Cystic component larger in larger lesions.
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| **Small lesions may be solid.
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| Image:
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| *[http://www.flickr.com/photos/bc_the_path/2510239905/in/photostream/ Warthin tumour (flickr.com)].
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| ===Microscopic===
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| Features:
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| * Papillae (nipple-shaped structures) with a two rows of pink (eosinophilic) epithelial cells (with cuboidal basal cells and columnar luminal cells) -- '''key feature'''.
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| * Fibrous capsule - pink & homogenous on [[H&E stain]].
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| * Cystic space filled with debris ''in situ'' (not [[necrosis]]).
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| * Lymphoid stroma.
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| Notes:
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| *+/-Squamous differentiation.
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| *+/-Goblet cell differentiation.
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| DDx:
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| *Lymphoepithelial cyst.
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| **Cyst within a lymph node.
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| ====Images====
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| <gallery>
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| Image:Papillary_cystadenoma_lymphomatosum3.jpg | Warthin tumour - high mag. (WC/Nephron)
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| Image:Papillary_cystadenoma_lymphomatosum2.jpg | Warthin tumour - intermed. mag. (WC/Nephron)
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| </gallery>
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| ==Sebaceous adenoma== | | ==Sebaceous adenoma== |