Difference between revisions of "Germ cell tumours"

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Germ cell tumours (view source)

Revision as of 23:26, 13 July 2013

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→‎Gonadoblastoma: redirect
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==Gonadoblastoma==
==Gonadoblastoma==
===General===
{{Main|Gonadoblastoma}}
*Associated with abnormal sexual development.
*Often coexist with a [[dysgerminoma]].
*A mixed tumour that consists of (1) primitive germ cells and (2) sex cord elements.


===Gross===
*+/-Cystic.
===Microscopic===
Features:<ref name=Ref_PBoD1104>{{Ref PBoD|1104}}</ref>
*Immature germ cells resembling Sertoli cells or granulosa cells.
**Sertoli cells = moderate cytoplasm in a trabecular or tubular architecture.
**Granulosa cells = form follicle-like structures.
***May form nests.
*Primitive germ cells resemble those of a [[dysgerminoma]].
**Polygonal cells with a central nucleus, squared-off nuclear membrane and clear cytoplasm.
*+/-Calcification (very common).
*+/-Eosinophilic basement membrane material between the (primitive) germ cells and support cells.<ref>URL: [http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/]. Accessed on: 11 September 2011.</ref>
====Images====
www:
*[http://www.webpathology.com/image.asp?n=40&Case=532 Gonadoblastoma - low mag. (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=532&n=42 Gonadoblastoma - high mag. (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=532&n=44 Gonadoblastoma - high mag. (webpathology.com)].
*[http://www.flickr.com/photos/ckrishnan/3972431774/in/photostream/ Gonadoblastoma - low mag. (flickr.com)].
*[http://www.flickr.com/photos/ckrishnan/3972432404/in/photostream/ Gonadoblastoma - intermed. mag. (flickr.com)].
*[http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ Gonadoblastoma - high mag. (flickr.com)].
*[http://path.upmc.edu/cases/case356.html Gonadoblastoma - several cases (upmc.edu)].
<gallery>
Image:Gonadoblastoma_-_intermed_mag.jpg | Gonadoblastoma - intermed. mag. (WC/Nephron)
Image:Gonadoblastoma_-_b_-_high_mag.jpg | Gonadoblastoma - high mag. (WC/Nephron)
</gallery>
==Polyembryoma==
==Polyembryoma==
===General===
===General===
Michael
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