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Difference between revisions of "Pilomatricoma"
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| Micro = "ghost" cells, foreign body-type giant cells | | Micro = "ghost" cells, foreign body-type giant cells | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[squamous cell carcinoma]], pilomatrix carcinoma, [[basal cell carcinoma]], [[epidermal inclusion cyst]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
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It is also known as '''calcifying epithelioma of Malherbe'''.<ref>{{Ref Derm|387}}</ref> | It is also known as '''calcifying epithelioma of Malherbe'''.<ref>{{Ref Derm|387}}</ref> | ||
==General== | |||
*Benign skin tumour. | *Benign skin tumour. | ||
*Most common solid skin tumour of children.<ref name=emed1058965>URL: [http://emedicine.medscape.com/article/1058965-overview http://emedicine.medscape.com/article/1058965-overview]. Accessed on: 10 September 2011.</ref> | *Most common solid skin tumour of children.<ref name=emed1058965>URL: [http://emedicine.medscape.com/article/1058965-overview http://emedicine.medscape.com/article/1058965-overview]. Accessed on: 10 September 2011.</ref> | ||
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*Surgical excision.<ref name=emed1058965>[http://emedicine.medscape.com/article/1058965-overview http://emedicine.medscape.com/article/1058965-overview]</ref> | *Surgical excision.<ref name=emed1058965>[http://emedicine.medscape.com/article/1058965-overview http://emedicine.medscape.com/article/1058965-overview]</ref> | ||
==Microscopic== | |||
Features:<ref name=emed1058965dx>URL: [http://emedicine.medscape.com/article/1058965-diagnosis http://emedicine.medscape.com/article/1058965-diagnosis]. Accessed on: 10 September 2011.</ref> | Features:<ref name=emed1058965dx>URL: [http://emedicine.medscape.com/article/1058965-diagnosis http://emedicine.medscape.com/article/1058965-diagnosis]. Accessed on: 10 September 2011.</ref> | ||
*Nodular circumscribed lower dermis/subcutaneous adipose lesion; thus, usu. surrounded by connective tissue. | *Nodular circumscribed lower dermis/subcutaneous adipose lesion; thus, usu. surrounded by connective tissue. | ||
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*Keratin a prominent feature on cytology - lots of orange stuff. | *Keratin a prominent feature on cytology - lots of orange stuff. | ||
*May ossify. | *May ossify. | ||
DDx: | DDx: | ||
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*[[Squamous cell carcinoma]]. | *[[Squamous cell carcinoma]]. | ||
*[[Basal cell carcinoma]]. | *[[Basal cell carcinoma]]. | ||
===Images=== | |||
<gallery> | |||
Image:Pilomatrixoma_-_high_mag.jpg | Pilomatrixoma - high mag. (WC/Nephron) | |||
Image:Pilomatrixoma_-_intermed_mag.jpg | Pilomatrixoma - intermed. mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.bccancer.bc.ca/HPI/CE/cytotechnology/cytosleuthquiz/nongyne/ngcase02.htm Pilomatrixoma - cytology (bccancer.bc.ca)]. | |||
*[http://www.dermrounds.com/photo/1980062:Photo:431 Pilomatrixoma - histology (dermrounds.com)]. | |||
===Sign out=== | ===Sign out=== | ||