Difference between revisions of "Germ cell tumours"

Germ cell tumours (view source)

1,132 bytes removed , 07:24, 3 July 2013

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 ==Embryonal carcinoma==
-===General===
+{{Main|Embryonal carcinoma}}
-*Affects young adults.
-**May be seen in women.
-===Microscopic===
-Features:<ref name=Ref_GUP549>{{Ref GUP|549}}</ref>
-#Nucleoli - '''key feature'''.
-#Vesicular nuclei (clear, empty appearing nuclei) - '''key feature'''.
-#Nuclei overlap.
-#[[Necrosis]] - common.
-#*Not commonly present in seminoma.
-#Indistinct cell borders
-#Mitoses - common.
-#Variable architecture:
-#*Tubulopapillary.
-#*Glandular.
-#*Solid.
-#*Embryoid bodies - ball of cells in surrounded by empty space on three sides.
-Notes:
-*Cytoplasmic staining variable (eosinophilic to basophilic).
-DDx:
-*[[Yolk sac tumour]].
-====Images====
-<gallery>
-Image:Embryonal_carcinoma_-_very_high_mag_-_cropped.jpg | Embryonal carcinoma - very high mag. - cropped (WC/Nephron)
-Image:Embryonal_carcinoma_-_high_mag.jpg | Embryonal carcinoma - high mag. (WC/Nephron)
-</gallery>
-<gallery>
-Image:Embryonal_carcinoma_high_mag.jpg | Embryonal carcinoma - high mag. (WC/Nephron)
-Image:Embryonal_carcinoma_intermed_mag.jpg | Embryonal carcinoma - intermed. mag. (WC/Nephron)
-Image:Embryonal_carcinoma_low_mag.jpg | Embryonal carcinoma - low mag. (WC/Nephron)
-</gallery>
-===IHC===
-*AE1/AE3 +ve.
-*CD30 +ve.
 ==Choriocarcinoma==