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Difference between revisions of "Prostate cancer"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Prostate cancer with Gleason pattern 4 low mag.jpg | |||
| Width = | |||
| Caption = Prostate carcinoma. [[H&E stain]]. | |||
| Micro = major criteria: abnormal architecture (increased gland density, usu. small circular glands, "infiltrative growth" pattern), basal cells lost, cytological abnormalities (nuclear enlargement, nucleoli); minor criteria: nuclear hyperchromasia, wispy blue mucin, pink amorphous secretions, intraluminal crystalloid, amphophilic cytoplasm, adjacent [[HGPIN]], mitoses | |||
| Subtypes = | |||
| LMDDx = [[high-grade prostatic intraepithelial neoplasia]], [[atypical small acinar proliferation]] (biopsy only), [[prostatic atrophy]], [[seminal vesicle]], [[basal cell hyperplasia of the prostate|basal cell hyperplasia]], others | |||
| Stains = | |||
| IHC = PSA +ve, PSAP +Ve, AMACR +ve, p63 -ve, CK34betaE12 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[prostate gland]] | |||
| Assdx = | |||
| Syndromes = | |||
| Signs = firm, nodular prostate on digital rectal exam | |||
| Symptoms = often asymptomatic | |||
| Prevalence = very common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = good-to-poor (depends on Gleason score and stage) | |||
| Other = | |||
| ClinDDx = prostatitis | |||
}} | |||
This article deals with '''prostate [[cancer]]'''. | This article deals with '''prostate [[cancer]]'''. | ||