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Difference between revisions of "Thyroid gland"
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→Microscopic
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Features: | Features: | ||
*Nuclear changes - '''key feature'''. | *Nuclear changes - '''key feature'''. | ||
*#"Shrivelled nuclei"/"raisin" like nuclei, nuclei with a wavy ("textured") nuclear membrane -- usu. easy to find. | *#"Shrivelled nuclei"/"raisin" like nuclei, nuclei with a wavy ("textured", convoluted) nuclear membrane -- usu. easy to find. | ||
*#[[Nuclear pseudoinclusions]] -- usu. harder to find; have high [[specificity]] (nuclear pseudoinclusions appear as a result of the | *#[[Nuclear pseudoinclusions]] -- usu. harder to find; have high [[specificity]] (nuclear pseudoinclusions appear as a result of the very convoluted nuclear membrane wrapping around parts of the cytoplasm; true nuclear inclusions in contrast are seen only in viral infections). | ||
*#Nuclear grooves, seen as a result of the highly "textured" nuclear membrane. | *#Nuclear grooves, seen as a result of the highly "textured" nuclear membrane. | ||
*#Nuclear clearing (only on permanent section) - also known as "Orphan Annie eyes". | *#Nuclear clearing (only on permanent section) - also known as "Orphan Annie eyes". | ||