Difference between revisions of "Soft tissue lesions"

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Soft tissue lesions (view source)

Revision as of 22:49, 2 June 2013

379 bytes removed ,  22:49, 2 June 2013
+image
(+image)
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*Others.
*Others.


Images:
====Images====
*[http://commons.wikimedia.org/w/index.php?title=File:Pleomorphic_undifferentiated_sarcoma_-_very_high_mag.jpg PUS - high mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Pleomorphic_undifferentiated_sarcoma_-_intermed_mag.jpg PUS - intermed. mag. (WC)].
Image:Pleomorphic_undifferentiated_sarcoma_-_very_high_mag.jpg | PUS - high mag. (WC/Nephron)
 
Image:Pleomorphic_undifferentiated_sarcoma_-_intermed_mag.jpg | PUS - intermed. mag. (WC/Nephron)
</gallery>
====Subclassification====
====Subclassification====
Pleomorphic sarcoma (PS) is subclassified the following way:<ref name=Ref_WMSP_613-4>{{Ref WMSP|613-4}}</ref>
Pleomorphic sarcoma (PS) is subclassified the following way:<ref name=Ref_WMSP_613-4>{{Ref WMSP|613-4}}</ref>
Line 352: Line 353:
*The first impression may be that it is [[granuloma|granulomatous inflammation]]; however, the cytoplasm doesn't fit (it isn't bubbly and it isn't sheet-like), and the nuclei aren't quite right (few footprint shaped nuclei).
*The first impression may be that it is [[granuloma|granulomatous inflammation]]; however, the cytoplasm doesn't fit (it isn't bubbly and it isn't sheet-like), and the nuclei aren't quite right (few footprint shaped nuclei).


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Angiomatoid_fibrous_histiocytoma_-_intermed_mag.jpg AFH - intermed. mag. (WC)].
Image:Angiomatoid_fibrous_histiocytoma_-_intermed_mag.jpg | AFH - intermed. mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Angiomatoid_fibrous_histiocytoma_-_high_mag.jpg AFH - high mag. (WC)].
Image:Angiomatoid_fibrous_histiocytoma_-_high_mag.jpg | AFH - high mag. (WC/Nephron)
*www:
</gallery>
**[http://www.sarcomaimages.com/index.php?v=Angiomatoid-Fibrous-Histiocytoma AFH (sarcomaimages.com)].
www:
*[http://www.sarcomaimages.com/index.php?v=Angiomatoid-Fibrous-Histiocytoma AFH (sarcomaimages.com)].
**[http://jcp.bmj.com/content/63/2/124/F1.large.jpg AFH (bmj.com)].<ref name=pmid20154033>{{Cite journal  | last1 = Matsumura | first1 = T. | last2 = Yamaguchi | first2 = T. | last3 = Tochigi | first3 = N. | last4 = Wada | first4 = T. | last5 = Yamashita | first5 = T. | last6 = Hasegawa | first6 = T. | title = Angiomatoid fibrous histiocytoma including cases with pleomorphic features analysed by fluorescence in situ hybridisation. | journal = J Clin Pathol | volume = 63 | issue = 2 | pages = 124-8 | month = Feb | year = 2010 | doi = 10.1136/jcp.2009.072256 | PMID = 20154033 | url = http://jcp.bmj.com/content/63/2/124.full }}
**[http://jcp.bmj.com/content/63/2/124/F1.large.jpg AFH (bmj.com)].<ref name=pmid20154033>{{Cite journal  | last1 = Matsumura | first1 = T. | last2 = Yamaguchi | first2 = T. | last3 = Tochigi | first3 = N. | last4 = Wada | first4 = T. | last5 = Yamashita | first5 = T. | last6 = Hasegawa | first6 = T. | title = Angiomatoid fibrous histiocytoma including cases with pleomorphic features analysed by fluorescence in situ hybridisation. | journal = J Clin Pathol | volume = 63 | issue = 2 | pages = 124-8 | month = Feb | year = 2010 | doi = 10.1136/jcp.2009.072256 | PMID = 20154033 | url = http://jcp.bmj.com/content/63/2/124.full }}
</ref>
</ref>
**[http://path.upmc.edu/cases/case512.html AFH - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case512.html AFH - several images (upmc.edu)].


===IHC===
===IHC===
Line 403: Line 405:
*[[Myxoma]].
*[[Myxoma]].


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Aggressive_angiomyxoma_-_intermed_mag.jpg Aggressive angiomyxoma - intermed. mag. (WC)].
Image:Aggressive_angiomyxoma_-_intermed_mag.jpg | Aggressive angiomyxoma - intermed. mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Aggressive_angiomyxoma_-_very_high_mag.jpg Aggressive angiomyxoma - very high mag. (WC)].
Image:Aggressive_angiomyxoma_-_very_high_mag.jpg | Aggressive angiomyxoma - very high mag. (WC/Nephron)
*www:
</gallery>
**[http://www.webpathology.com/image.asp?n=1&Case=99 Aggressive angiomyxoma - low mag. (webpathology.com)].
www:
*[http://www.webpathology.com/image.asp?n=1&Case=99 Aggressive angiomyxoma - low mag. (webpathology.com)].
**[http://www.webpathology.com/image.asp?case=99&n=2 Aggressive angiomyxoma - high mag. (webpathology.com)].
**[http://www.webpathology.com/image.asp?case=99&n=2 Aggressive angiomyxoma - high mag. (webpathology.com)].
**[http://path.upmc.edu/cases/case538.html Aggressive angiomyxoma - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case538.html Aggressive angiomyxoma - several images (upmc.edu)].


===IHC===
===IHC===
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*[[Granuloma annulare]].
*[[Granuloma annulare]].


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Epithelioid_sarcoma_-_intermed_mag.jpg ES - intermed. mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Epithelioid_sarcoma_-_high_mag.jpg ES - high mag. (WC)].
Image:Epithelioid_sarcoma_-_intermed_mag.jpg | ES - intermed. mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Epithelioid_sarcoma_-_smarcb1_-_high_mag.jpg ES - SMARCB1/INI1 - high mag. (WC)].
Image:Epithelioid_sarcoma_-_high_mag.jpg | ES - high mag. (WC/Nephron)
Image:Epithelioid_sarcoma_-_smarcb1_-_high_mag.jpg | ES - SMARCB1/INI1 - high mag. (WC/Nephron)
</gallery>
www:
*[http://path.upmc.edu/cases/case594.html ES - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case594.html ES - several images (upmc.edu)].


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*[[Rhabdomyosarcoma]], alveolar - usu. does not have sheets of rhabdoid cells.
*[[Rhabdomyosarcoma]], alveolar - usu. does not have sheets of rhabdoid cells.


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Alveolar_soft_part_sarcoma_-_low_mag.jpg ASPS - low mag. (WC)].
Image:Alveolar_soft_part_sarcoma_-_low_mag.jpg | ASPS - low mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Alveolar_soft_part_sarcoma_-_intermed_mag.jpg ASPS - intermed. mag. (WC)].
Image:Alveolar_soft_part_sarcoma_-_intermed_mag.jpg | ASPS - intermed. mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Alveolar_soft_part_sarcoma_-2-_very_high_mag.jpg ASPS - very high mag. (WC)].
Image:Alveolar_soft_part_sarcoma_-2-_very_high_mag.jpg | ASPS - very high mag. (WC/Nephron)
*www:
</gallery>
**[http://www.webpathology.com/image.asp?case=508&n=10 ASPS - PAS (webpathology.com)].
www:
*[http://www.webpathology.com/image.asp?case=508&n=10 ASPS - PAS (webpathology.com)].


===Stains===
===Stains===
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*Usu. abundant mitoses.
*Usu. abundant mitoses.
*+/-Necrosis.
*+/-Necrosis.
Images:
*[http://en.wikipedia.org/wiki/File:Desmoplastic_small_round_cell_tumour_-_intermed_mag.jpg DSRCT - intermed. mag. (WC)].
*[http://en.wikipedia.org/wiki/File:Desmoplastic_small_round_cell_tumour_-_very_high_mag.jpg DSRCT - very high mag. (WC)].


DDx:
DDx:
Line 586: Line 589:
*Solid variant of [[alveolar RMS]].
*Solid variant of [[alveolar RMS]].
**Nests in alveolar RMS have round edges.
**Nests in alveolar RMS have round edges.
====Images====
<gallery>
Image:Desmoplastic_small_round_cell_tumour_-_intermed_mag.jpg | DSRCT - intermed. mag. (WC/Nephron)
Image:Desmoplastic_small_round_cell_tumour_-_very_high_mag.jpg | DSRCT - very high mag. (WC/Nephron)
</gallery>


===IHC===
===IHC===
Line 628: Line 637:
*Carcinoma.
*Carcinoma.


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma_-_intermed_mag.jpg Clear cell sarcoma - intermed. mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma_-_very_high_mag.jpg Clear cell sarcoma - very high mag. (WC)].
Image:Clear_cell_sarcoma_-_intermed_mag.jpg | Clear cell sarcoma - intermed. mag. (WC)
*[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma.Image12.jpg Clear cell sarcoma (WC/Gardner)].
Image:Clear_cell_sarcoma_-_very_high_mag.jpg | Clear cell sarcoma - very high mag. (WC)
 
Image:Clear_cell_sarcoma.Image12.jpg | Clear cell sarcoma (WC/Gardner)
</gallery>
===IHC===
===IHC===
Features:<ref name=pmid18300804/>
Features:<ref name=pmid18300804/>
Line 701: Line 711:
**Can be difficult.
**Can be difficult.


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Monophasic_synovial_sarcoma_-_intermed_mag.jpg Monophasic synovial sarcoma with staghorn vessels - intermed. mag. (WC)].
*Image:Monophasic_synovial_sarcoma_-_intermed_mag.jpg | Monophasic synovial sarcoma with staghorn vessels - intermed. mag. (WC/Nephron)
**[http://www.scielo.br/img/revistas/ibju/v30n3/3a06f03.jpg Synovial sarcoma (scielo.br)].
</gallery>
www:
*[http://www.scielo.br/img/revistas/ibju/v30n3/3a06f03.jpg Synovial sarcoma (scielo.br)].
*[http://www.humpath.com/spip.php?page=article&id_article=1965 Synovial sarcoma - collection of images (humpath.com)].
*[http://www.humpath.com/spip.php?page=article&id_article=1965 Synovial sarcoma - collection of images (humpath.com)].
**[http://path.upmc.edu/cases/case292.html Synovial sarcoma - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case292.html Synovial sarcoma - several images (upmc.edu)].
*www:
*[http://radiographics.rsna.org/content/26/5/1543/F14.expansion.html Biphasic SS (radiographics.rsna.org)].
**[http://radiographics.rsna.org/content/26/5/1543/F14.expansion.html Biphasic SS (radiographics.rsna.org)].
*[http://radiographics.rsna.org/content/26/5/1543.long Monophasic SS (radiographics.rsna.org)].
**[http://radiographics.rsna.org/content/26/5/1543.long Monophasic SS (radiographics.rsna.org)].


===IHC===
===IHC===
Line 776: Line 787:
*May mimic [[small cell carcinoma]], large cell lymphomas ([[DLBCL]], [[ALCL]]), [[small round cell tumour]]s.
*May mimic [[small cell carcinoma]], large cell lymphomas ([[DLBCL]], [[ALCL]]), [[small round cell tumour]]s.


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Chloroma_-_high_mag.jpg Chloroma - high mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Chloroma_-_very_high_mag.jpg Chloroma - very high mag. (WC)].
Image:Chloroma_-_high_mag.jpg | Chloroma - high mag. (WC)
Image:Chloroma_-_very_high_mag.jpg | Chloroma - very high mag. (WC)
</gallery>
www:
*[http://path.upmc.edu/cases/case306/micro.html Granulocytic sarcoma - several crappy images (upmc.edu)].
*[http://path.upmc.edu/cases/case306/micro.html Granulocytic sarcoma - several crappy images (upmc.edu)].
*[http://path.upmc.edu/cases/case379.html Myeloid sarcoma - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case379.html Myeloid sarcoma - several images (upmc.edu)].
Michael
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