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| fern-like arrangement of epithelium (low power), nucleoli, surrounded by muscle, +/- nuclear inclusions | | fern-like arrangement of epithelium (low power), nucleoli, surrounded by muscle, +/- nuclear inclusions | ||
| involvement by cancer changes staging, lipofuscin may be present in prostate, often has marked nuc. size var.; location: usu. base of prostate | | involvement by cancer changes staging, lipofuscin may be present in prostate, often has marked nuc. size var.; location: usu. base of prostate | ||
| [ | | [[Image:Seminal_vesicle_high_mag.jpg |thumb|150px|center|SV - high mag. (WC)]] | ||
|- | |- | ||
| Radiation effect | | Radiation effect | ||
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| no nuclear atypia, normal gland arch. | | no nuclear atypia, normal gland arch. | ||
| clinical mimic of cancer (elevated PSA); usu. not a problem for the pathologist | | clinical mimic of cancer (elevated PSA); usu. not a problem for the pathologist | ||
| [ | | [[Image:Inflammation_of_prostate.jpg|thumb|150px|center| Prostatic inflammation. (WC)] | ||
|- | |- | ||
| [[Vasitis nodosa]] | | [[Vasitis nodosa]] | ||
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*One gland is not enough to call Gleason 4. | *One gland is not enough to call Gleason 4. | ||
Images | =====Images===== | ||
<gallery> | |||
Image:Prostate_cancer_with_Gleason_pattern_4_low_mag.jpg | Gleason pattern 4 - cribriform. (WC) | |||
Image:Gleason_4_and_5_intermed_mag.jpg | Gleason pattern 4 - small glands & Gleason pattern 5 - single cells. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.nature.com/modpathol/journal/v17/n3/fig_tab/3800050f9.html#figure-title Glomeruloid pattern (nature.com)]. | *[http://www.nature.com/modpathol/journal/v17/n3/fig_tab/3800050f9.html#figure-title Glomeruloid pattern (nature.com)]. | ||
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</ref> | </ref> | ||
Images | =====Images===== | ||
*[ | <gallery> | ||
*[Image:Gleason_4_and_5_intermed_mag.jpg | Gleason pattern 4 - small glands & Gleason pattern 5 - single cells (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.webpathology.com/image.asp?n=17&Case=20 Gleason pattern 5 - sheeting (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=17&Case=20 Gleason pattern 5 - sheeting (webpathology.com)]. | ||
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