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Difference between revisions of "Basics"
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Image: | Image: | ||
<gallery> | |||
Image:Ulcers,_fissures,_and_erosions.svg | Ulcers and erosions - schematic. (WC) | |||
</gallery> | |||
====Microscopic - erosion==== | ====Microscopic - erosion==== | ||
Features - require 1 and 2: | Features - require 1 and 2: | ||
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*Apoptotic cell -- has nuclear condensation (pyknosis), eosinophilic cytoplasm. | *Apoptotic cell -- has nuclear condensation (pyknosis), eosinophilic cytoplasm. | ||
Images: | ====Images==== | ||
<gallery> | |||
Image:Atypical_mitosis.jpg| Mitoses and an atypical mitosis. (WC) | |||
Image:Tripolar_Mitosis_-_breast_carcinoma.jpg| Tripolar mitosis. (WC) | |||
</gallery> | |||
www: | |||
*[http://education.vetmed.vt.edu/Curriculum/VM8054/Labs/Lab4/IMAGES/MITOSIS%20IN%20GUT.JPG Mitoses (vetmed.vt.edu)]. | *[http://education.vetmed.vt.edu/Curriculum/VM8054/Labs/Lab4/IMAGES/MITOSIS%20IN%20GUT.JPG Mitoses (vetmed.vt.edu)]. | ||
*[http://www.flickr.com/photos/euthman/426956752/ Starburst mitosis (flicker.com)]. | *[http://www.flickr.com/photos/euthman/426956752/ Starburst mitosis (flicker.com)]. | ||
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*Alican blue-PAS stain. | *Alican blue-PAS stain. | ||
Images: | ====Images==== | ||
<gallery> | |||
Image:Signet_ring_cells_5.jpg |SRCs - H&E stain. (WC/Nephron) | |||
Image:Gastric_signet_ring_cell_carcinoma_histopatholgy_(2)_PAS_stain.jpg | SRCs - AL-PAS stain. (WC) | |||
Image:Gastric_signet_ring_cell_carcinoma_histopatholgy_(1).jpg | SRC - H&E stain. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.engravingarts.com/sales/LVX2.jpg Signet rings (engravingarts.com)]. | *[http://www.engravingarts.com/sales/LVX2.jpg Signet rings (engravingarts.com)]. | ||
===Necrosis=== | ===Necrosis=== | ||
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*[http://www.nature.com/bmt/journal/v39/n9/fig_tab/1705646f1.html Necrosis (nature.com)]. | *[http://www.nature.com/bmt/journal/v39/n9/fig_tab/1705646f1.html Necrosis (nature.com)]. | ||
*[http://moon.ouhsc.edu/kfung/jty1/Com08/Com08Image/Com801-1-09.gif Necrosis (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Com08/Com801-1-Diss.htm http://moon.ouhsc.edu/kfung/jty1/Com08/Com801-1-Diss.htm]. Accessed on: 3 November 2010.</ref> | *[http://moon.ouhsc.edu/kfung/jty1/Com08/Com08Image/Com801-1-09.gif Necrosis (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Com08/Com801-1-Diss.htm http://moon.ouhsc.edu/kfung/jty1/Com08/Com801-1-Diss.htm]. Accessed on: 3 November 2010.</ref> | ||
<gallery> | |||
Image:Cat_scratch_disease_-_very_high_mag.jpg | Necrosis in cat scratch disease. (WC/Nephron) | |||
Image:Histiocytic_necrotizing_lymphadenitis_-_very_high_mag.jpg | Necrosis in histiocytic necrotizing lymphadenitis. (WC/Nephron) | |||
Image:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg | Necrosis in SLE lymphadenopathy. (WC/Nephron) | |||
</gallery> | |||
==Granulomas== | ==Granulomas== | ||
*Granulomas can be elusive to the novice. | *Granulomas can be elusive to the novice. | ||
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===Features that assist one in finding granulomas=== | ===Features that assist one in finding granulomas=== | ||
#Collection of cells that have abundant bubbly cytoplasm - '''most useful feature'''. | #Collection of cells that have abundant bubbly cytoplasm - '''most useful feature'''. | ||
#'''Multinucleated [[giant cells]]''' - these are easy to identify if you've seen some before. | #'''Multinucleated [[giant cells]]''' - these are easy to identify if you've seen some before. | ||
#*Individual/singular multinucleated giant cells are not diagnostic of a granuloma... but should raise one's suspicion of one being present. | #*Individual/singular multinucleated giant cells are not diagnostic of a granuloma... but should raise one's suspicion of one being present. | ||
#Necrosis - too much pink (on H&E stained sections). | #Necrosis - too much pink (on H&E stained sections). | ||
Notes: | Notes: | ||
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**If there are no macrophages... it's a ''lymphoid nodule''. | **If there are no macrophages... it's a ''lymphoid nodule''. | ||
Images: | |||
<gallery> | |||
Image:Granuloma_20x.jpg |Granulomas showing abundant bubbly cytoplasm. (WC) | |||
Image:Asteroid_body_intermed_mag.jpg |Granulomas with multinucleated giant cells in sarcoidosis. (WC) | |||
Image:Necrogran10x.jpg|Granuloma with necrosis. (WC) | |||
</gallery> | |||
====As a list==== | ====As a list==== | ||
Features:<ref>GS. 26 January 2010.</ref> | Features:<ref>GS. 26 January 2010.</ref> | ||
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=====Images===== | =====Images===== | ||
<gallery> | <gallery> | ||
Image:Cardiac_amyloidosis_high_mag_he.jpg | Cardiac amyloid (WC/Nephron) | Image:Cardiac_amyloidosis_high_mag_he.jpg | Cardiac amyloid. (WC/Nephron) | ||
Image:Laminations_in_a_thrombus_-_high_mag.jpg | Fibrin in a thrombus (WC/Nephron) | Image:Laminations_in_a_thrombus_-_high_mag.jpg | Fibrin in a thrombus. (WC/Nephron) | ||
Image:Ovarian_fibroma_-_high_mag.jpg | Collagen in an ovarian fibroma (WC/Nephron) | Image:Ovarian_fibroma_-_high_mag.jpg | Collagen in an ovarian fibroma. (WC/Nephron) | ||
Image:Glatte_Muskelzellen.jpg | Smooth muscle (WC/Polarlys) | Image:Glatte_Muskelzellen.jpg | Smooth muscle. (WC/Polarlys) | ||
</gallery> | </gallery> | ||