Difference between revisions of "Colorectal tumours"

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Colorectal tumours (view source)

Revision as of 04:10, 20 May 2013

174 bytes removed ,  04:10, 20 May 2013
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(+images)
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*The (soft tissue) radial margins, as present in TMEs and right hemicolectomies, should be inked.<ref>URL: [http://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=13954 http://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=13954]. Accessed on: 6 February 2013. </ref><ref name=pmid15790712>{{Cite journal  | last1 = Bateman | first1 = AC. | last2 = Carr | first2 = NJ. | last3 = Warren | first3 = BF. | title = The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 426-8 | month = Apr | year = 2005 | doi = 10.1136/jcp.2004.019802 | PMID = 15790712 }}</ref>
*The (soft tissue) radial margins, as present in TMEs and right hemicolectomies, should be inked.<ref>URL: [http://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=13954 http://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=13954]. Accessed on: 6 February 2013. </ref><ref name=pmid15790712>{{Cite journal  | last1 = Bateman | first1 = AC. | last2 = Carr | first2 = NJ. | last3 = Warren | first3 = BF. | title = The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 426-8 | month = Apr | year = 2005 | doi = 10.1136/jcp.2004.019802 | PMID = 15790712 }}</ref>


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Colon_cancer_2.jpg CRC - gross (WC)].
<gallery>
*[http://pathinfo.wikia.com/wiki/File:Rectum_anterior_view.jpg Rectum - anterior view (wikia.com)].
Image:Colon_cancer_2.jpg | CRC - gross. (WC)
*[http://pathinfo.wikia.com/wiki/File:Rectum_lateral_view.jpg Rectum - lateral view (wikia.com)].
Image:Rectum - anterior view.jpg | Rectum - anterior view. (WC)
*[http://pathinfo.wikia.com/wiki/File:Rectum_inking.jpg Rectum - inked (wikia.com)].
Image:Rectum - lateral_view.jpg | Rectum - lateral view. (WC)
Image:Rectum - anterior and lateral - inked.jpg| Rectum - inked. (WC)
</gallery>
*[http://pathinfo.wikia.com/wiki/File:Rectum_opened.jpg Rectum - opened (wikia.com)].
*[http://pathinfo.wikia.com/wiki/File:Rectum_opened.jpg Rectum - opened (wikia.com)].


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**Sheets.
**Sheets.


Images:
====Images====
www:
*[http://www.flickr.com/photos/euthman/2480926690/in/set-72057594114099781 Colorectal adenocarcinoma (flickr.com/euthman)].
*[http://www.flickr.com/photos/euthman/2480926690/in/set-72057594114099781 Colorectal adenocarcinoma (flickr.com/euthman)].
*[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_coli.jpg Colorectal adenocarcinoma (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Colonic_mucinous_adenocarcinoma_-_low_mag.jpg Mucinous adenocarcinoma of the colon - low mag. (WC)].
Image:Adenocarcinoma_coli.jpg | Colorectal adenocarcinoma. (WC)
 
Image:Colonic_mucinous_adenocarcinoma_-_low_mag.jpg | Mucinous adenocarcinoma of the colon - low mag. (WC/Nephron)
</gallery>
====Grading====
====Grading====
Based on component composed of glands:
Based on component composed of glands:
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* † Definitions vary substantially - some authors consider lymphocytes adjacent to the tumour (in the stroma around the tumour cells) "intratumoural".<reF name=pmid9349235>{{Cite journal  | last1 = Ropponen | first1 = KM. | last2 = Eskelinen | first2 = MJ. | last3 = Lipponen | first3 = PK. | last4 = Alhava | first4 = E. | last5 = Kosma | first5 = VM. | title = Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. | journal = J Pathol | volume = 182 | issue = 3 | pages = 318-24 | month = Jul | year = 1997 | doi = 10.1002/(SICI)1096-9896(199707)182:3318::AID-PATH8623.0.CO;2-6 | PMID = 9349235 |URL = http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291096-9896%28199707%29182:3%3C318::AID-PATH862%3E3.0.CO;2-6/pdf}}</ref>
* † Definitions vary substantially - some authors consider lymphocytes adjacent to the tumour (in the stroma around the tumour cells) "intratumoural".<reF name=pmid9349235>{{Cite journal  | last1 = Ropponen | first1 = KM. | last2 = Eskelinen | first2 = MJ. | last3 = Lipponen | first3 = PK. | last4 = Alhava | first4 = E. | last5 = Kosma | first5 = VM. | title = Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. | journal = J Pathol | volume = 182 | issue = 3 | pages = 318-24 | month = Jul | year = 1997 | doi = 10.1002/(SICI)1096-9896(199707)182:3318::AID-PATH8623.0.CO;2-6 | PMID = 9349235 |URL = http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291096-9896%28199707%29182:3%3C318::AID-PATH862%3E3.0.CO;2-6/pdf}}</ref>


Images:
======Images======
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Tumour_infiltrating_lymphocytes_in_colorectal_carcinoma_-_high_mag.jpg TILs - high mag. (WC/Nephron)].
Image:Tumour_infiltrating_lymphocytes_in_colorectal_carcinoma_-_high_mag.jpg | TILs - high mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Tumour_infiltrating_lymphocytes_in_colorectal_carcinoma_-_very_high_mag.jpg TILs - very high mag. (WC/Nephron)].
Image:Tumour_infiltrating_lymphocytes_in_colorectal_carcinoma_-_very_high_mag.jpg | TILs - very high mag. (WC/Nephron)
*www:
</gallery>
**[http://jcp.bmjjournals.com/content/62/8/679/F3.large.jpg TILs in endometrial carcinoma (bmjjournals.com)].<ref name=pmid19638537>{{Cite journal  | last1 = Garg | first1 = K. | last2 = Soslow | first2 = RA. | title = Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma. | journal = J Clin Pathol | volume = 62 | issue = 8 | pages = 679-84 | month = Aug | year = 2009 | doi = 10.1136/jcp.2009.064949 | PMID = 19638537 | URL = http://jcp.bmjjournals.com/content/62/8/679.full?related-urls=yes&legid=jclinpath;62/8/679 }}</ref>
www:
**[http://ajcp.ascpjournals.org/content/134/3/478/F2.expansion.html TILs in CRC (ascpjournals.org)].<ref name=pmid20716806/>
*[http://jcp.bmjjournals.com/content/62/8/679/F3.large.jpg TILs in endometrial carcinoma (bmjjournals.com)].<ref name=pmid19638537>{{Cite journal  | last1 = Garg | first1 = K. | last2 = Soslow | first2 = RA. | title = Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma. | journal = J Clin Pathol | volume = 62 | issue = 8 | pages = 679-84 | month = Aug | year = 2009 | doi = 10.1136/jcp.2009.064949 | PMID = 19638537 | URL = http://jcp.bmjjournals.com/content/62/8/679.full?related-urls=yes&legid=jclinpath;62/8/679 }}</ref>
*[http://ajcp.ascpjournals.org/content/134/3/478/F2.expansion.html TILs in CRC (ascpjournals.org)].<ref name=pmid20716806/>


===IHC===
===IHC===
Michael
48,830

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