Difference between revisions of "Gastrointestinal tract polyps"

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===Microscopic===
===Microscopic===
One of the two following:
One of the two following:
#Usual morphology - features:<ref name=pmid22827760>{{Cite journal  | last1 = Kimura | first1 = R. | last2 = Fujimori | first2 = T. | last3 = Ichikawa | first3 = K. | last4 = Ajioka | first4 = Y. | last5 = Ueno | first5 = H. | last6 = Ohkura | first6 = Y. | last7 = Kashida | first7 = H. | last8 = Togashi | first8 = K. | last9 = Yao | first9 = T. | title = Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study. | journal = Pathol Int | volume = 62 | issue = 8 | pages = 525-31 | month = Aug | year = 2012 | doi = 10.1111/j.1440-1827.2012.02840.x | PMID = 22827760 }}</ref>
#Dysplasia and evidence of invasion - features:<ref name=pmid22827760>{{Cite journal  | last1 = Kimura | first1 = R. | last2 = Fujimori | first2 = T. | last3 = Ichikawa | first3 = K. | last4 = Ajioka | first4 = Y. | last5 = Ueno | first5 = H. | last6 = Ohkura | first6 = Y. | last7 = Kashida | first7 = H. | last8 = Togashi | first8 = K. | last9 = Yao | first9 = T. | title = Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study. | journal = Pathol Int | volume = 62 | issue = 8 | pages = 525-31 | month = Aug | year = 2012 | doi = 10.1111/j.1440-1827.2012.02840.x | PMID = 22827760 }}</ref>
#*Nuclear changes seen in adenomatous polyps - malignant-appearing cells.
#*Nuclear changes seen in adenomatous polyps - malignant-appearing cells.
#**Enlarged nuclei.
#**Enlarged nuclei.
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#**Round-shape ''or'' cigar-shaped and pseudostratified.
#**Round-shape ''or'' cigar-shaped and pseudostratified.
#*Architectural changes - usually those of high-grade dysplasia:
#*Architectural changes - usually those of high-grade dysplasia:
#**Cribriforming.
#**Cribriforming - most common.
#**Papillary tufting.
#**Papillary tufting.
#**Budding.
#**Budding.
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#*#Malignant-appearing cells in the submucosa.
#*#Malignant-appearing cells in the submucosa.
#*#*Pseudoinvasion must be excluded.  
#*#*Pseudoinvasion must be excluded.  
#*#[[Desmoplastic response]].  
#*#[[Desmoplastic stromal response]].  
#*#*Spindle cells with:
#*#*Spindle cells with:
#*#**Large nuclei (nucleus ~ size of a plasma cell).
#*#**Large nuclei (nucleus ~ size of a plasma cell).
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Image:Cecal_adenocarcinoma.jpg | Colorectal carcinoma. (WC/Nephron)
Image:Cecal_adenocarcinoma.jpg | Colorectal carcinoma. (WC/Nephron)
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