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m (→Anatomy & histology: tweak) |
(→Adrenal cortical adenoma: re-work) |
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*Hormonally active. | *Hormonally active. | ||
*Non-incidental finding. (???) | *Non-incidental finding. (???) | ||
Notes: | |||
*[[Cushing disease]] is due to the ACTH over-production by the [[pituitary]]. | |||
*In cortisol producing tumours (''Cushing syndrome''): atrophy of the non-hyperplastic cortex (due to feedback inhibition from the [[pituitary gland]]). | |||
===Microscopic=== | ===Microscopic=== | ||
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*May have foci of [[necrosis]]/degeneration and nuclear atypia. | *May have foci of [[necrosis]]/degeneration and nuclear atypia. | ||
In aldosterone producing tumours: | Note: | ||
*May extend outside of the capsule (should ''not'' be diagnosed as ''adrenal cortical carcinoma''). | *In aldosterone producing tumours: | ||
*No atrophy of non-hyperplastic cortex | **May extend outside of the capsule (should ''not'' be diagnosed as ''[[adrenal cortical carcinoma]]''). | ||
**No atrophy of non-hyperplastic cortex. | |||
DDx: | |||
* | *Adrenal cortical nodule.<ref name=Ref_EP200>{{Ref EP|200}}</ref> | ||
*[[Adrenal cortical | *[[Adrenal cortical hyperplasia]]. | ||
**Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref> | **Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref> | ||
*[[Adrenal cortical carcinoma]]. | |||
==Pheochromocytoma== | ==Pheochromocytoma== |
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