Difference between revisions of "Adrenal gland"

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78 bytes added ,  19:48, 13 May 2013
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*Hormonally active.
*Hormonally active.
*Non-incidental finding. (???)
*Non-incidental finding. (???)
Notes:
*[[Cushing disease]] is due to the ACTH over-production by the [[pituitary]].
*In cortisol producing tumours (''Cushing syndrome''): atrophy of the non-hyperplastic cortex (due to feedback inhibition from the [[pituitary gland]]).


===Microscopic===
===Microscopic===
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*May have foci of [[necrosis]]/degeneration and nuclear atypia.
*May have foci of [[necrosis]]/degeneration and nuclear atypia.


In aldosterone producing tumours:
Note:
*May extend outside of the capsule (should ''not'' be diagnosed as ''adrenal cortical carcinoma'').
*In aldosterone producing tumours:
*No atrophy of non-hyperplastic cortex.
**May extend outside of the capsule (should ''not'' be diagnosed as ''[[adrenal cortical carcinoma]]'').
 
**No atrophy of non-hyperplastic cortex.
In cortisol producing tumours (''Cushing syndrome''):
*Atrophy of the non-hyperplastic cortex (due to feedback inhibition from the [[pituitary gland]]).


Notes:
DDx:
*[[Cushing disease]] is due to the ACTH over-production by the [[pituitary]].
*Adrenal cortical nodule.<ref name=Ref_EP200>{{Ref EP|200}}</ref>
*[[Adrenal cortical hyperplasia|Adrenal hyperplasia]] vs. adrenal adenoma:
*[[Adrenal cortical hyperplasia]].
**Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref>
**Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref>
*[[Adrenal cortical carcinoma]].


==Pheochromocytoma==
==Pheochromocytoma==
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