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Difference between revisions of "Kidney tumours"
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→Classic
(→IHC) |
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Features - classic type (3 P's [[mnemonic]]):<ref>{{Ref PBoD|1016-7}}</ref><ref name=Ref_GUP293>{{Ref GUP|293}}</ref> | Features - classic type (3 P's [[mnemonic]]):<ref>{{Ref PBoD|1016-7}}</ref><ref name=Ref_GUP293>{{Ref GUP|293}}</ref> | ||
*Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs". | *Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs". | ||
*Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''. | *Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''. | ||
*Periphery of cell distinct, i.e. cell membrane is easy to discern. | *Periphery of cell distinct, i.e. cell membrane is easy to discern. | ||
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*May have [[psammoma bodies]]. | *May have [[psammoma bodies]]. | ||
*May be described as "plant-like"; plant cells have (thick) cell walls. | *May be described as "plant-like"; plant cells have (thick) cell walls. | ||
*Perinuclear clear is often somewhat patchy, i.e. it is usually not present in very tumour cell. | |||
DDx: | DDx: | ||