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Difference between revisions of "Lymphoma"
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→Primary mediastinal B-cell lymphoma
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*www: | *www: | ||
**[http://path.upmc.edu/cases/case371.html PMBL - several images (upmc.edu)]. | **[http://path.upmc.edu/cases/case371.html PMBL - several images (upmc.edu)]. | ||
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<pre> | |||
MASS, ANTERIOR MEDIASTINAL, CORE BIOPSY: | |||
- LARGE B-CELL LYMPHOMA IN A FIBROTIC BACKGROUND WITH NECROSIS, SEE COMMENT | |||
COMMENT: | |||
Morphology: | |||
Tumour cells: size ~2x a mature lymphocyte, a moderate quantity of grey/basophilic | |||
cytoplasm, no clear cells are identified. | |||
Cells intermixed with tumour: mature lymphocytes, rare eosinophils. | |||
Architecture: no gland formation, discohesive, no follicles apparent, extensive fibrosis. | |||
Tumour cells: | |||
POSITIVE: CD45, CD20, CD10, BCL-6, BCL-2. | |||
NEGATIVE: pankeratin, PLAP, CD3, CD30. | |||
Ki-67: 50% of large (lymphoid) cells. | |||
</pre> | |||
==Anaplastic large cell lymphoma== | ==Anaplastic large cell lymphoma== | ||