48,830
edits
m (→Etiology) |
|||
Line 358: | Line 358: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*''Helicobacter pylori'': | *Helicobacter organisms - '''key feature'''. | ||
**Usually have v-shape (seagull-like shape). | **''Helicobacter pylori'': | ||
***May have a curved shape (comma-like shape) or U-shape.<ref name=pmid21290743>{{Cite journal | last1 = Mobley | first1 = HLT. | last2 = Mendz | first2 = GL. | last3 = Hazell | first3 = SL. | last4 = Andersen | first4 = LP. | last5 = Wadström | first5 = T. | title = Basic Bacteriology and Culture | journal = | volume = | issue = | pages = | month = | year = | doi = | PMID = 21290743 | url = http://www.ncbi.nlm.nih.gov/books/NBK2444/}} </ref> | ***Usually have v-shape (seagull-like shape). | ||
*''Helicobacter heilmannii'':<ref name=pmid16224223 >{{Cite journal | last1 = Singhal | first1 = AV. | last2 = Sepulveda | first2 = AR. | title = Helicobacter heilmannii gastritis: a case study with review of literature. | journal = Am J Surg Pathol | volume = 29 | issue = 11 | pages = 1537-9 | month = Nov | year = 2005 | doi = | PMID = 16224223 }}</ref> | ****May have a curved shape (comma-like shape) or U-shape.<ref name=pmid21290743>{{Cite journal | last1 = Mobley | first1 = HLT. | last2 = Mendz | first2 = GL. | last3 = Hazell | first3 = SL. | last4 = Andersen | first4 = LP. | last5 = Wadström | first5 = T. | title = Basic Bacteriology and Culture | journal = | volume = | issue = | pages = | month = | year = | doi = | PMID = 21290743 | url = http://www.ncbi.nlm.nih.gov/books/NBK2444/}} </ref> | ||
**Corkscrew appearance. | **''Helicobacter heilmannii'':<ref name=pmid16224223 >{{Cite journal | last1 = Singhal | first1 = AV. | last2 = Sepulveda | first2 = AR. | title = Helicobacter heilmannii gastritis: a case study with review of literature. | journal = Am J Surg Pathol | volume = 29 | issue = 11 | pages = 1537-9 | month = Nov | year = 2005 | doi = | PMID = 16224223 }}</ref> | ||
***Corkscrew appearance. | |||
*Inflammation - usually ''moderate chronic active''. | |||
**Clusters of (lamina propria) [[plasma cell]]s. | |||
**[[Neutrophil]]s, numerous, classically intraepithelial. | |||
Tips: | Tips: | ||
#One needs to look at 400x magnification. Even at 400x they are possible to miss. | |||
#*Helicobacter are damn small. They are smaller than the nucleus of the gastric foveollar cell. | |||
#Look for mucus - they preferentially reside there. | |||
#*This is usually close to the opening of the gastric pits. | |||
#Helicobacter are found in groups. When you see several that are the same size and shape you can be sure they are real. | |||
Notes: | Notes: | ||
Line 376: | Line 380: | ||
DDx: | DDx: | ||
*Dirt - variable size. | *Dirt - material has a variable size. | ||
*Contamination from oropharynx - bacilli straight, not associated with gastric mucosa. | |||
Images: | Images: |
edits