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(→Sessile serrated adenoma: +gross) |
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===General=== | ===General=== | ||
*Colonic lesion. | *Colonic lesion. | ||
*May be seen in the context of ''[[serrated polyposis syndrome]]''. | *May be seen in the context of ''[[serrated polyposis syndrome]]''. | ||
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*Thought to lead to colorectal cancer through a different pathway that most tumours in the left colon/rectum. | *Thought to lead to colorectal cancer through a different pathway that most tumours in the left colon/rectum. | ||
*''Microvesicular [[hyperplastic polyp]]s'' are hypothesized to be the the precursor of SSAs.<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 }}</ref> | *''Microvesicular [[hyperplastic polyp]]s'' are hypothesized to be the the precursor of SSAs.<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 }}</ref> | ||
===Gross=== | |||
Features:<ref name=pmid22710576/> | |||
*Flat lesions with a "mucous cap". | |||
*More common in the proximal colon. | |||
Image: | |||
*[http://www.nature.com/ajg/journal/v105/n12/fig_tab/ajg2010330f1.html SSA - endoscopy (nature.com)].<ref name=pmid21131934>{{cite journal |author=Rex DK, Hewett DG, Snover DC |title=Editorial: Detection targets for colonoscopy: from variable detection to validation |journal=Am. J. Gastroenterol. |volume=105 |issue=12 |pages=2665–9 |year=2010 |month=December |pmid=21131934 |doi=10.1038/ajg.2010.330 |url=}}</ref> | |||
===Microscopic=== | ===Microscopic=== |
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