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Difference between revisions of "Testis"
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→Sertoli cell nodule
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*Benign proliferation of Sertoli cells - associated with cryptorchidism (undescended testis). | *Benign proliferation of Sertoli cells - associated with cryptorchidism (undescended testis). | ||
*Not composed of a clonal cell population, i.e. ''not'' neoplastic; thus, technically, should not be called an ''adenoma''.<ref name=Ref_DCHH227>{{Ref DCHH|227}}</ref> | *Not composed of a clonal cell population, i.e. ''not'' neoplastic; thus, technically, should not be called an ''adenoma''.<ref name=Ref_DCHH227>{{Ref DCHH|227}}</ref> | ||
*Usually an incidental finding.<ref name=pmid21107095>{{Cite journal | last1 = Vallangeon | first1 = BD. | last2 = Eble | first2 = JN. | last3 = Ulbright | first3 = TM. | title = Macroscopic sertoli cell nodule: a study of 6 cases that presented as testicular masses. | journal = Am J Surg Pathol | volume = 34 | issue = 12 | pages = 1874-80 | month = Dec | year = 2010 | doi = 10.1097/PAS.0b013e3181fcab70 | PMID = 21107095 }}</ref> | |||
===Gross=== | |||
*Usually an incidental finding, rarely presents as a testicular mass. | |||
===Microscopic=== | ===Microscopic=== | ||
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*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_high_mag.jpg Sertoli cell nodule - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_high_mag.jpg Sertoli cell nodule - high mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_low_mag.jpg Sertoli cell nodule - low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_low_mag.jpg Sertoli cell nodule - low mag. (WC)]. | ||
===IHC=== | |||
Features:<ref name=pmid21107095/> | |||
*Alpha-inhibin +ve (5/5 cases). | |||
*OCT3/4 -ve (5/5 cases). | |||
==Sertoli cell tumour== | ==Sertoli cell tumour== | ||