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***Adipocytes - increased with age, may be used to help differentiate from thyroid - '''key feature'''. | ***Adipocytes - increased with age, may be used to help differentiate from thyroid - '''key feature'''. | ||
Parathyroid cell types: | |||
{| class="wikitable" | {| class="wikitable" | ||
| '''Name''' | | '''Name''' | ||
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| ? | | ? | ||
|} | |} | ||
Notes: | Notes - table: | ||
*Cytoplasmic staining varies considerably on H&E preparations - it may vary from hyperchromatic<ref>[http://www.deltagen.com/target/histologyatlas/atlas_files/endocrine/parathyroid_and_thyroid_glands_20x.jpg http://www.deltagen.com/target/histologyatlas/atlas_files/endocrine/parathyroid_and_thyroid_glands_20x.jpg]</ref> to clear to eosinophilic<ref>[http://instruction.cvhs.okstate.edu/Histology/HistologyReference/hrendo.htm http://instruction.cvhs.okstate.edu/Histology/HistologyReference/hrendo.htm]</ref>. | *Cytoplasmic staining varies considerably on H&E preparations - it may vary from hyperchromatic<ref>[http://www.deltagen.com/target/histologyatlas/atlas_files/endocrine/parathyroid_and_thyroid_glands_20x.jpg http://www.deltagen.com/target/histologyatlas/atlas_files/endocrine/parathyroid_and_thyroid_glands_20x.jpg]</ref> to clear to eosinophilic<ref>[http://instruction.cvhs.okstate.edu/Histology/HistologyReference/hrendo.htm http://instruction.cvhs.okstate.edu/Histology/HistologyReference/hrendo.htm]</ref>. | ||
*Chief cells tend to stain more intensely than oxyphil cells. | *Chief cells tend to stain more intensely than oxyphil cells. | ||
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**Gland-like/follicular-like arrangement -- much smaller than normal follicles of | **Gland-like/follicular-like arrangement -- much smaller than normal follicles of | ||
**Occasional cell with rim of clear cytoplasm (oxyphil?). | **Occasional cell with rim of clear cytoplasm (oxyphil?). | ||
**Nuclei are different: | |||
***Slightly larger than in lymphocytes (1.2-1.5x the size) | |||
***Stippled chromatin (unlike lymphocytes). | |||
Images: | Images: |
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