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*"Large" round ''or'' polygonal nuclei. | *"Large" round ''or'' polygonal nuclei. | ||
**Size in relation to normal often not defined. | **Size in relation to normal often not defined. | ||
***Rakheja ''et al.'' say >= 5x a lymphocyte.<ref name=pmid11900581>{{Cite journal | last1 = Rakheja | first1 = D. | last2 = Hoang | first2 = MP. | last3 = Sharma | first3 = S. | last4 = Albores-Saavedra | first4 = J. | title = Intratubular embryonal carcinoma. | journal = Arch Pathol Lab Med | volume = 126 | issue = 4 | pages = 487-90 | month = Apr | year = 2002 | doi = 10.1043/0003-9985(2002)1260487:IEC2.0.CO;2 | PMID = 11900581 | url = http://www.archivesofpathology.org/doi/full/10.1043/0003-9985(2002)126%3C0487:IEC%3E2.0.CO;2 }}</ref> | ***Rakheja ''et al.'' say >= 5x a lymphocyte for intratubular embryonal carcinoma.<ref name=pmid11900581>{{Cite journal | last1 = Rakheja | first1 = D. | last2 = Hoang | first2 = MP. | last3 = Sharma | first3 = S. | last4 = Albores-Saavedra | first4 = J. | title = Intratubular embryonal carcinoma. | journal = Arch Pathol Lab Med | volume = 126 | issue = 4 | pages = 487-90 | month = Apr | year = 2002 | doi = 10.1043/0003-9985(2002)1260487:IEC2.0.CO;2 | PMID = 11900581 | url = http://www.archivesofpathology.org/doi/full/10.1043/0003-9985(2002)126%3C0487:IEC%3E2.0.CO;2 }}</ref> | ||
**Polygonal nuclei = squared-off nuclear membrane. | **Polygonal nuclei = squared-off nuclear membrane. | ||
*Prominent nucleoli - '''key feature'''. | *Prominent nucleoli - '''key feature'''. | ||
*Clear cytoplasm. | *Clear cytoplasm. | ||
*+/-Cells fill the tubule. | *+/-Cells fill the tubule. | ||
DDx: | DDx: | ||
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*www: | *www: | ||
**[http://www.webpathology.com/image.asp?case=30&n=1 ITGCN (webpathology.com)]. | **[http://www.webpathology.com/image.asp?case=30&n=1 ITGCN (webpathology.com)]. | ||
**[http://www.archivesofpathology.org/na101/home/literatum/publisher/pinnacle/journals/content/arpa/2002/15432165-126.4/0003-9985%282002%29126%3C0487%3Aiec%3E2.0.co%3B2/production/images/large/i1543-2165-126-4-487-f01.jpeg | **[http://www.archivesofpathology.org/na101/home/literatum/publisher/pinnacle/journals/content/arpa/2002/15432165-126.4/0003-9985%282002%29126%3C0487%3Aiec%3E2.0.co%3B2/production/images/large/i1543-2165-126-4-487-f01.jpeg Intratubular embryonal carcinoma (archivesofpathology.org)].<ref name=pmid11900581/> | ||
===IHC=== | ===IHC=== |
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