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Difference between revisions of "Prostate cancer"
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→Prostatectomy grossing
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===Prostatectomy grossing=== | ===Prostatectomy grossing=== | ||
There are several consensus papers on grossing by the '' | There are several consensus papers on grossing prostatectomies by the ''International Society of Urological Pathology'' (ISUP). | ||
*Prostate gland:<ref name=pmid20834234>{{Cite journal | last1 = Samaratunga | first1 = H. | last2 = Montironi | first2 = R. | last3 = True | first3 = L. | last4 = Epstein | first4 = JI. | last5 = Griffiths | first5 = DF. | last6 = Humphrey | first6 = PA. | last7 = van der Kwast | first7 = T. | last8 = Wheeler | first8 = TM. | last9 = Srigley | first9 = JR. | title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 6-15 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.178 | PMID = 20834234 }}</ref> | *Prostate gland:<ref name=pmid20834234>{{Cite journal | last1 = Samaratunga | first1 = H. | last2 = Montironi | first2 = R. | last3 = True | first3 = L. | last4 = Epstein | first4 = JI. | last5 = Griffiths | first5 = DF. | last6 = Humphrey | first6 = PA. | last7 = van der Kwast | first7 = T. | last8 = Wheeler | first8 = TM. | last9 = Srigley | first9 = JR. | title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 6-15 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.178 | PMID = 20834234 }}</ref> | ||
**[[Embedding in toto]] is not required. | **[[Embedding in toto]] is not required. | ||
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**The prostate should be painted -- to mark the margins. | **The prostate should be painted -- to mark the margins. | ||
**Sectioning should be done after fixation. | **Sectioning should be done after fixation. | ||
**The prostate should be weighted after | **The prostate should be weighted after trimming the seminal vesicles. | ||
**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin). | **The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin). | ||
*Lymph nodes and seminal vesicles (SV):<ref name=pmid20818343>{{Cite journal | last1 = Berney | first1 = DM. | last2 = Wheeler | first2 = TM. | last3 = Grignon | first3 = DJ. | last4 = Epstein | first4 = JI. | last5 = Griffiths | first5 = DF. | last6 = Humphrey | first6 = PA. | last7 = van der Kwast | first7 = T. | last8 = Montironi | first8 = R. | last9 = Delahunt | first9 = B. | title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 39-47 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.160 | PMID = 20818343 }}</ref> | *Lymph nodes and seminal vesicles (SV):<ref name=pmid20818343>{{Cite journal | last1 = Berney | first1 = DM. | last2 = Wheeler | first2 = TM. | last3 = Grignon | first3 = DJ. | last4 = Epstein | first4 = JI. | last5 = Griffiths | first5 = DF. | last6 = Humphrey | first6 = PA. | last7 = van der Kwast | first7 = T. | last8 = Montironi | first8 = R. | last9 = Delahunt | first9 = B. | title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 39-47 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.160 | PMID = 20818343 }}</ref> | ||