Difference between revisions of "Gastrointestinal tract polyps"

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===Microscopic===
===Microscopic===
#Nuclear changes at the surface (of the mucosa) - '''key feature'''.
#Nuclear changes at the surface of the mucosa - '''key feature'''.
#*Cigar-shaped (elongated) nucleus (usu. length:width > 3:1) - '''key feature'''.
#*Size and shape ''or'' size change:
#**Normal nuclei are round.
#**Cigar-shaped (elongated) nucleus (usu. length:width > 3:1) with nuclear hyperchromasia (more blue).
#*Nuclear crowding/pseudostratification - '''key feature'''.
#**Large round nuclei +/- vesicular appearance (clearing) -- nuclei have white space.
#*Nuclear hyperchromasia (more blue).
#*Nuclear crowding/pseudostratification - '''important'''.
#*+/-Loss of nuclear polarity (nuclei no longer on basement membrane).
#*+/-Loss of nuclear polarity (nuclei no longer on basement membrane).
#Loss/decrease of goblet cells (common).
#Loss/decrease of goblet cells (common).
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