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Difference between revisions of "Gastrointestinal tract polyps"
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Gastrointestinal tract polyps (view source)
Revision as of 12:14, 22 March 2013
, 12:14, 22 March 2013→Microscopic: minimal extent
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*Crypt branching. | *Crypt branching. | ||
*Horizontal crypts (crypts that run along the muscular mucosae). | *Horizontal crypts (crypts that run along the muscular mucosae). | ||
Minimal extent: | |||
*An expert panel lead by ''Rex'' states that one unequivocally altered crypt should prompt calling SSA.<ref name=pmid22710576>{{Cite journal | last1 = Rex | first1 = DK. | last2 = Ahnen | first2 = DJ. | last3 = Baron | first3 = JA. | last4 = Batts | first4 = KP. | last5 = Burke | first5 = CA. | last6 = Burt | first6 = RW. | last7 = Goldblum | first7 = JR. | last8 = Guillem | first8 = JG. | last9 = Kahi | first9 = CJ. | title = Serrated lesions of the colorectum: review and recommendations from an expert panel. | journal = Am J Gastroenterol | volume = 107 | issue = 9 | pages = 1315-29; quiz 1314, 1330 | month = Sep | year = 2012 | doi = 10.1038/ajg.2012.161 | PMID = 22710576 }}</ref> | |||
*The ''Stanford Surgical Pathology Criteria'' note that the WHO requires three adjacent crypts to be abnormal.<ref>URL: [http://surgpathcriteria.stanford.edu/gitumors/sessile-serrated-polyp-adenoma/ http://surgpathcriteria.stanford.edu/gitumors/sessile-serrated-polyp-adenoma/]. Accessed on: 26 September 2012.</ref> | |||
Notes: | Notes: | ||
*Typically do not have nuclear atypia, i.e. no nuclear crowding, no nuclear hyperchromasia, no cigar-shaped nuclei. | *Typically do not have nuclear atypia, i.e. no nuclear crowding, no nuclear hyperchromasia, no cigar-shaped nuclei. | ||
**SSAs with nuclear atypia may be referred to as ''advanced sessile serrated adenomas''. | **SSAs with nuclear atypia may be referred to as ''advanced sessile serrated adenomas''. | ||
DDx: | DDx: | ||