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Difference between revisions of "Dermatologic neoplasms"
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→Sebaceous carcinoma
m (→Micro) |
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====Grading==== | ====Grading==== | ||
Three tier system:<ref name=Ref_Derm431-2>{{Ref Derm|431-2}}</ref> | Three tier system:<ref name=Ref_Derm431-2>{{Ref Derm|431-2}}</ref> | ||
*Well-differentiated. | *Well-differentiated - sebocytes predominant. | ||
*Moderately differentiated. | *Moderately differentiated - sebocytes are easily recognized but a minor component. | ||
*Poorly differentiated. | *Poorly differentiated - sebocytes are rare. | ||
===IHC=== | ===IHC=== | ||
| Line 573: | Line 573: | ||
The lesion is completely excised in the plane of section. | The lesion is completely excised in the plane of section. | ||
=====Poor differentiated===== | |||
The sections show well-circumscribed dermal nests of basaloid cells with peripheral | |||
palisading, surrounded by a dense fibrous stroma, that extend from the skin surface almost | |||
to the adipose tissue. The basaloid cells have moderate nuclear atypia with occasional monstrous cells. Mitotic activity is abundant and atypical mitoses are present. The nests contain rare cells with pale, fluffy-appearing cytoplasm, suggestive of sebocytes. | |||
==Microcystic adnexal carcinoma== | ==Microcystic adnexal carcinoma== | ||