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Difference between revisions of "Non-invasive breast carcinoma"
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Non-invasive breast carcinoma (view source)
Revision as of 11:17, 19 March 2013
, 11:17, 19 March 2013→Ductal carcinoma in situ: w
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**Architecture suggestive of DCIS - see ''[[Subtypes of DCIS]]''. | **Architecture suggestive of DCIS - see ''[[Subtypes of DCIS]]''. | ||
*Nuclear changes: | *Nuclear changes: | ||
**Nuclear enlargement - at least 2-3x size of RBC - '''key feature'''. | **Nuclear enlargement - at least 2-3x size of [[RBC]] - '''key feature'''. | ||
***Compared to RBCs to grade DCIS - see ''[[Grading DCIS]]''. | ***Compared to RBCs to grade DCIS - see ''[[Grading DCIS]]''. | ||
****Compare sizes of nuclei if you cannot find RBCs. | ****Compare sizes of nuclei if you cannot find RBCs. | ||
| Line 178: | Line 178: | ||
Graded 1-3 (low-high)<ref>URL: [http://surgpathcriteria.stanford.edu/breast/dcis/ http://surgpathcriteria.stanford.edu/breast/dcis/]. Accessed on: 4 August 2011.</ref> - compare lesional nuclei to one another. | Graded 1-3 (low-high)<ref>URL: [http://surgpathcriteria.stanford.edu/breast/dcis/ http://surgpathcriteria.stanford.edu/breast/dcis/]. Accessed on: 4 August 2011.</ref> - compare lesional nuclei to one another. | ||
*Grade 1: | *Grade 1: | ||
**Nuclei 2-3x size of RBC. | **Nuclei 2-3x size of [[RBC]]. | ||
**No necrosis. | **No necrosis. | ||
*Grade 2: | *Grade 2: | ||
**Nuclei 2-3x size of RBC. | **Nuclei 2-3x size of RBC. | ||
**+/-Necrosis. | **+/-[[Necrosis]]. | ||
*Grade 3: | *Grade 3: | ||
**Nuclei >3x size of RBC. | **Nuclei >3x size of RBC. | ||