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Difference between revisions of "Malignant melanoma"
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| confined to epidermis, nuclear atypia | | confined to epidermis, nuclear atypia | ||
| melanocyte enlargement, nuclear hyperchromasia, +/- melanocytes above suprapapillary plate (above basal layer) = "Pagetoid spread" | | melanocyte enlargement, nuclear hyperchromasia, +/- melanocytes above suprapapillary plate (above basal layer) = "Pagetoid spread" | ||
| melanocytic hyperplasia, pagetoid Spitz nevus | | melanocytic hyperplasia, pagetoid Spitz nevus, [[dysplastic nevus]]<ref name=pmid15953373>{{Cite journal | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref> | ||
| [http://path.upmc.edu/cases/case97/micro.html (upmc.edu)], [http://commons.wikimedia.org/wiki/File:Lentigo_maligna_-_high_mag.jpg (WC)] | | [http://path.upmc.edu/cases/case97/micro.html (upmc.edu)], [http://commons.wikimedia.org/wiki/File:Lentigo_maligna_-_high_mag.jpg (WC)] | ||
| ''lentigo maligna'' (LM) is melanoma in situ<ref name=pmid16681656>{{Cite journal | last1 = McKenna | first1 = JK. | last2 = Florell | first2 = SR. | last3 = Goldman | first3 = GD. | last4 = Bowen | first4 = GM. | title = Lentigo maligna/lentigo maligna melanoma: current state of diagnosis and treatment. | journal = Dermatol Surg | volume = 32 | issue = 4 | pages = 493-504 | month = Apr | year = 2006 | doi = 10.1111/j.1524-4725.2006.32102.x | PMID = 16681656 }}</ref> on sun damaged skin; LM should '''not''' be confused with ''lentigo maligna melanoma'' (LMM) | | ''lentigo maligna'' (LM) is melanoma in situ<ref name=pmid16681656>{{Cite journal | last1 = McKenna | first1 = JK. | last2 = Florell | first2 = SR. | last3 = Goldman | first3 = GD. | last4 = Bowen | first4 = GM. | title = Lentigo maligna/lentigo maligna melanoma: current state of diagnosis and treatment. | journal = Dermatol Surg | volume = 32 | issue = 4 | pages = 493-504 | month = Apr | year = 2006 | doi = 10.1111/j.1524-4725.2006.32102.x | PMID = 16681656 }}</ref> on sun damaged skin; LM should '''not''' be confused with ''lentigo maligna melanoma'' (LMM) | ||