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*Nucleoli should be visible with the 20x objective. | *Nucleoli should be visible with the 20x objective. | ||
**If one uses the 40x objective... one over calls. | **If one uses the 40x objective... one over calls. | ||
*May need IHC for cancer versus HGPIN. | *May need IHC for cancer versus HGPIN. | ||
*Nucleoli should be present in >= 10% of cells in a gland to call it HGPIN.<ref>{{Ref Amin|3-55}}</ref> | |||
**This criterium is not required by all pathologists. | |||
DDx: | DDx: |
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