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Difference between revisions of "Chronic granulomatous disease"
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Chronic granulomatous disease (view source)
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'''Chronic granulomatous disease''', abbreviated '''CGD''', is a specific diagnosis; it should ''not'' be understood as a granulomatous disease that is of a long duration. | '''Chronic granulomatous disease''', abbreviated '''CGD''', is a specific diagnosis; it should ''not'' be understood as a granulomatous disease that is of a long duration. | ||
CGD is disorder of | CGD is disorder of [[neutrophil]]s,<ref name=pmid19098859/> and typically leads to widespread [[granuloma]]s.<ref name=pmid21116026>{{cite journal |author=Seger RA |title=Chronic granulomatous disease: recent advances in pathophysiology and treatment |journal=Neth J Med |volume=68 |issue=11 |pages=334–40 |year=2010 |month=November |pmid=21116026 |doi= |url=}}</ref> | ||
==General== | ==General== | ||
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DDx: | DDx: | ||
*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.{{Cite journal | last1 = Marks | first1 = DJ. | last2 = Miyagi | first2 = K. | last3 = Rahman | first3 = FZ. | last4 = Novelli | first4 = M. | last5 = Bloom | first5 = SL. | last6 = Segal | first6 = AW. | title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. | journal = Am J Gastroenterol | volume = 104 | issue = 1 | pages = 117-24 | month = Jan | year = 2009 | doi = 10.1038/ajg.2008.72 | PMID = 19098859 }}</ref> | *[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.<ref name=pmid19098859>{{Cite journal | last1 = Marks | first1 = DJ. | last2 = Miyagi | first2 = K. | last3 = Rahman | first3 = FZ. | last4 = Novelli | first4 = M. | last5 = Bloom | first5 = SL. | last6 = Segal | first6 = AW. | title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. | journal = Am J Gastroenterol | volume = 104 | issue = 1 | pages = 117-24 | month = Jan | year = 2009 | doi = 10.1038/ajg.2008.72 | PMID = 19098859 }}</ref> | ||
==References== | ==References== | ||