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Difference between revisions of "Pancreas"
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→Pancreas neoplasms in a table: +sortable
(→Acinar cell carcinoma of the pancreas: +images) |
(→Pancreas neoplasms in a table: +sortable) |
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| Line 48: | Line 48: | ||
===Pancreas neoplasms in a table=== | ===Pancreas neoplasms in a table=== | ||
{| class="wikitable" | {| class="wikitable sortable" | ||
!| Type | !| Type | ||
!| Key feature | !| Key feature | ||
| Line 62: | Line 62: | ||
| cuboidal cells, clear cytoplasm | | cuboidal cells, clear cytoplasm | ||
| cystadenoma, borderline t., cystadenocarcinoma | | cystadenoma, borderline t., cystadenocarcinoma | ||
| [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_%281%29.jpg], [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_%282%29.jpg], [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_-_intermed_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_%281%29.jpg], [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_%282%29.jpg (WC)], [http://commons.wikimedia.org/wiki/File:Pancreatic_serous_cystadenoma_-_intermed_mag.jpg (WC)] | ||
| IHC? | | IHC? | ||
| cuboidal cells, clear cytoplasm, central nucleus | | cuboidal cells, clear cytoplasm, central nucleus | ||
| Line 82: | Line 82: | ||
| mucin, ovarian-like stroma | | mucin, ovarian-like stroma | ||
| cystadenoma, borderline t., cystadenocarcinoma | | cystadenoma, borderline t., cystadenocarcinoma | ||
| [http://commons.wikimedia.org/w/index.php?title=File:Benign_pancreatic_mucinous_cystic_neoplasm_-_intermed_mag.jpg], [http://commons.wikimedia.org/w/index.php?title=File:Benign_pancreatic_mucinous_cystic_neoplasm_-_high_mag.jpg] | | [http://commons.wikimedia.org/w/index.php?title=File:Benign_pancreatic_mucinous_cystic_neoplasm_-_intermed_mag.jpg (WC)], [http://commons.wikimedia.org/w/index.php?title=File:Benign_pancreatic_mucinous_cystic_neoplasm_-_high_mag.jpg (WC)] | ||
| IHC? | | IHC? | ||
| tall columnar mucin-producing cells, ovarian-like stroma | | tall columnar mucin-producing cells, ovarian-like stroma | ||
| Line 92: | Line 92: | ||
| eosinophilic intracytoplasmic globules | | eosinophilic intracytoplasmic globules | ||
| clear cell variant (cytoplasm clear) | | clear cell variant (cytoplasm clear) | ||
| [http://commons.wikimedia.org/w/index.php?title=File:Solid_pseudopapillary_tumour_-_intermed_mag.jpg], [http://jcp.bmj.com/content/61/11/1153/F1.large.jpg] | | [http://commons.wikimedia.org/w/index.php?title=File:Solid_pseudopapillary_tumour_-_intermed_mag.jpg (WC)], [http://jcp.bmj.com/content/61/11/1153/F1.large.jpg (bmj.com)] | ||
| beta-catenin +ve, E-cadherin +ve, <br>synaptophysin +ve, chromogranin -ve | | beta-catenin +ve, E-cadherin +ve, <br>synaptophysin +ve, chromogranin -ve | ||
| sheets of cells, focally loosely cohesive, eosinophilic cytoplasm, uniform nuclei with grooves | | sheets of cells, focally loosely cohesive, eosinophilic cytoplasm, uniform nuclei with grooves | ||
| Line 102: | Line 102: | ||
| irregular shaped glands, cytologic atypia | | irregular shaped glands, cytologic atypia | ||
| mucinous, spindle cell, mixed ductal-endocrine | | mucinous, spindle cell, mixed ductal-endocrine | ||
| [http://commons.wikimedia.org/wiki/File:Pancreas_adenocarcinoma_%284%29_Case_01.jpg], [http://commons.wikimedia.org/wiki/File:Pancreas_adenocarcinoma_%282%29_Case_01.jpg] | | [http://commons.wikimedia.org/wiki/File:Pancreas_adenocarcinoma_%284%29_Case_01.jpg (WC)], [http://commons.wikimedia.org/wiki/File:Pancreas_adenocarcinoma_%282%29_Case_01.jpg (WC)] | ||
| IHC? | | IHC? | ||
| glands, sheets, single cells, nuc. atypia, +/-mitoses, +/-[[necrosis]] | | glands, sheets, single cells, nuc. atypia, +/-mitoses, +/-[[necrosis]] | ||
| Line 109: | Line 109: | ||
| ampullary carcinoma, [[chronic pancreatitis]] | | ampullary carcinoma, [[chronic pancreatitis]] | ||
|- | |- | ||
| Pancreatoblastoma | | [[Pancreatoblastoma]] | ||
| squamoid nests, whorling | | squamoid nests, whorling | ||
| - | | - | ||
| | | [http://www.nature.com/modpathol/journal/v20/n1s/fig_tab/3800686f16.html#figure-title (nature.com)] | ||
| | | CK7 (acinar comp.), CK8, CK18, CK19 | ||
| squamoid nests of cells, whorling, nested growth, +/-keratinization | | squamoid nests of cells, whorling, nested growth, +/-keratinization | ||
| none | | none | ||
| Line 122: | Line 122: | ||
| acinar arch. | | acinar arch. | ||
| - | | - | ||
| [http://www.histopathology-india.net/acinar%20cell%20ca.JPG] | | [http://commons.wikimedia.org/wiki/File:Acinar_cell_carcinoma_of_the_pancreas_-_very_high_mag.jpg (WC)], [http://www.histopathology-india.net/acinar%20cell%20ca.JPG (histopathology-india.net)] | ||
| | | trypsin, lipase | ||
| nests or [[trabeculae]], nucleolus, mod. basophilic granular cytoplasm | | nests or [[trabeculae]], nucleolus, mod. basophilic granular cytoplasm | ||
| head (slight predilection) | | head (slight predilection) | ||