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Difference between revisions of "Asphyxial deaths"
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→Carbon monoxide: more
m (→Macroscopic: +ref) |
(→Carbon monoxide: more) |
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*CO binds to haemoglobin -- prevents oxygen from binding there. | *CO binds to haemoglobin -- prevents oxygen from binding there. | ||
===Gross findings=== | |||
*Salmon pink skin. | *Salmon pink skin. | ||
*CO level (blood test) elevated (? | |||
===Laboratory findings=== | |||
*CO level (blood test) elevated. | |||
COHb concentrations (by CO-oximetry):<ref name=pmid20348410>{{cite journal |author=Olson KN, Hillyer MA, Kloss JS, Geiselhart RJ, Apple FS |title=Accident or arson: is CO-oximetry reliable for carboxyhemoglobin measurement postmortem? |journal=Clin. Chem. |volume=56 |issue=4 |pages=515–9 |year=2010 |month=April |pmid=20348410 |doi=10.1373/clinchem.2009.131334 |url=http://www.clinchem.org/cgi/content/full/56/4/515}}</ref> | |||
*Smokers 10-15%. | |||
*Non-smokers <3%. | |||
*Fatal >50%. | |||
**Some say >35% % is fatal.<ref>TR. 28 September 2010.</ref> | |||
Notes: | |||
*Two different methods:<ref name=pmid16126621>{{cite journal |author=Boumba VA, Vougiouklakis T |title=Evaluation of the methods used for carboxyhemoglobin analysis in postmortem blood |journal=Int. J. Toxicol. |volume=24 |issue=4 |pages=275–81 |year=2005 |pmid=16126621 |doi=10.1080/10915810591007256 |url=}}</ref> | |||
*#Spectrophotometric methods - includes CO-oximeters. | |||
*#Gas chromatographic methods. | |||
*Spectrophotometric methods are considered good enough. | |||
*Gas chromatographic methods are considered the gold standard. | |||
==Manual strangulation== | ==Manual strangulation== | ||