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*Cytokeratins - (weak focal positivity) | *Cytokeratins - (weak focal positivity) | ||
==Intratubular germ cell neoplasia== | |||
*Considered the precursor lesion for germ cell tumours. | |||
*Not all germ cell tumours (GCTs) arise from ''intratubular germ cell neoplasia''. | |||
The following testicular GCTs do not arise from ITCGN: | |||
*[[Spermatocytic seminoma]],<ref>{{cite journal |author=Müller J, Skakkebaek NE, Parkinson MC |title=The spermatocytic seminoma: views on pathogenesis |journal=Int. J. Androl. |volume=10 |issue=1 |pages=147–56 |year=1987 |month=February |pmid=3583416 |doi= |url=}}</ref> and | |||
*[[Yolk sac tumour]]s (endodermal sinus tumour).<ref>{{cite journal |author=Manivel JC, Simonton S, Wold LE, Dehner LP |title=Absence of intratubular germ cell neoplasia in testicular yolk sac tumors in children. A histochemical and immunohistochemical study |journal=Arch. Pathol. Lab. Med. |volume=112 |issue=6 |pages=641–5 |year=1988 |month=June |pmid=2837162 |doi= |url=}}</ref> | |||
*Teratoma. (???) | |||
==Spermatocytic seminoma== | ==Spermatocytic seminoma== |
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