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*Minimal palisading. | *Minimal palisading. | ||
**Nuclei <3:1 = height:width. | **Nuclei <3:1 = height:width. | ||
*No nuclear pseudostratification. | *No nuclear pseudostratification. † | ||
*Deep part of crypt more hyperchromatic than superficial component. | *Deep part of crypt is more hyperchromatic than superficial component - '''important'''. | ||
**The surface should be lighter staining than the deeper aspect, i.e. the deeper glands are dark blue and the superficial gland are light blue. | |||
Note: | |||
* † May be seen in [[reactive changes]]. | |||
DDx (colorectal mucosa with minimal changes): | |||
*[[CMV colitis]]. | |||
*[[Cryptosporidiosis]]. | |||
*[[Intestinal spirochetosis]]. | |||
*[[Lymphocytic colitis]]. | |||
*[[Collagenous colitis]]. | |||
Images: | Images: | ||
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