Difference between revisions of "Fibroblastic/myofibroblastic tumours"

Fibroblastic/myofibroblastic tumours (view source)

767 bytes added , 20:48, 30 January 2013

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 Features:<ref>URL: [http://www.dermatologyoutlines.com/dermskintumornonmelanocytic.html#collagenousfibroma http://www.dermatologyoutlines.com/dermskintumornonmelanocytic.html#collagenousfibroma]. Accessed on: 19 March</ref><ref name=Ref_Sternberg4_161>{{Ref Sternberg4|161}}</ref>
 *Acellular stroma with abundant collagen.
+*Spindle cells or stellate cells.
 Notes:
 *'''No''' nuclear atypia.
+Images:
+*[http://www.webpathology.com/image.asp?case=458&n=1 Desmoplastic fibroma (webpathology.com)].
+*[http://www.ajronline.org/content/183/6/1766/F3.expansion Desmoplastic fibroma (ajronline.org)].
 ===IHC===
@@ Line 265: / Line 270: @@
 </ref>
 **+ve in [[desmoid-type fibromatosis]].
+===Molecular===
+*llq13 breakpoint described as being characteristic.<ref name=pmid22868002>{{Cite journal  | last1 = Trombetta | first1 = D. | last2 = Macchia | first2 = G. | last3 = Mandahl | first3 = N. | last4 = Nord | first4 = KH. | last5 = Mertens | first5 = F. | title = Molecular genetic characterization of the 11q13 breakpoint in a desmoplastic fibroma of bone. | journal = Cancer Genet | volume = 205 | issue = 7-8 | pages = 410-3 | month =  | year =  | doi = 10.1016/j.cancergen.2012.05.002 | PMID = 22868002 }}
+</ref>
 ==Calcifying fibrous tumour==