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Difference between revisions of "Gastrointestinal tract polyps"
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Gastrointestinal tract polyps (view source)
Revision as of 17:05, 23 January 2013
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===Microscopic=== | ===Microscopic=== | ||
One of the following: | One of the two following: | ||
#Usual morphology - features:<ref name=pmid22827760>{{Cite journal | last1 = Kimura | first1 = R. | last2 = Fujimori | first2 = T. | last3 = Ichikawa | first3 = K. | last4 = Ajioka | first4 = Y. | last5 = Ueno | first5 = H. | last6 = Ohkura | first6 = Y. | last7 = Kashida | first7 = H. | last8 = Togashi | first8 = K. | last9 = Yao | first9 = T. | title = Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study. | journal = Pathol Int | volume = 62 | issue = 8 | pages = 525-31 | month = Aug | year = 2012 | doi = 10.1111/j.1440-1827.2012.02840.x | PMID = 22827760 }}</ref> | #Usual morphology - features:<ref name=pmid22827760>{{Cite journal | last1 = Kimura | first1 = R. | last2 = Fujimori | first2 = T. | last3 = Ichikawa | first3 = K. | last4 = Ajioka | first4 = Y. | last5 = Ueno | first5 = H. | last6 = Ohkura | first6 = Y. | last7 = Kashida | first7 = H. | last8 = Togashi | first8 = K. | last9 = Yao | first9 = T. | title = Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study. | journal = Pathol Int | volume = 62 | issue = 8 | pages = 525-31 | month = Aug | year = 2012 | doi = 10.1111/j.1440-1827.2012.02840.x | PMID = 22827760 }}</ref> | ||
#*Nuclear changes seen in adenomatous polyps - malignant-appearing cells. | |||
#**Enlarged nuclei. | |||
#*Nuclear changes seen in adenomatous polyps. | |||
#**Enlarged. | |||
#**Chromatin hyperchromatic ''or'' vesicular. | #**Chromatin hyperchromatic ''or'' vesicular. | ||
#**Round- | #**Round-shape ''or'' cigar-shaped and pseudostratified. | ||
#*Architectural changes - usually those of high-grade dysplasia: | #*Architectural changes - usually those of high-grade dysplasia: | ||
#**Cribriforming. | #**Cribriforming. | ||
#**Papillary tufting. | #**Papillary tufting. | ||
#**Budding. | #**Budding. | ||
#**Sheeting. | |||
#*Deep involvement - one of the two following - '''key feature''': | |||
#*#Malignant-appearing cells in the submucosa. | |||
#*#*Pseudoinvasion must be excluded. | |||
#*#Desmoplastic response. | |||
#*#*Spindle cells with large nuclei. | |||
#*#**Nuclei ~ size of a plasma cell. | |||
#*#*Eosinophilic cytoplasm. | |||
#[[Signet ring cell carcinoma|Signet ring cells]]. | #[[Signet ring cell carcinoma|Signet ring cells]]. | ||