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Difference between revisions of "Placenta"
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→Perivillous fibrin deposition
(→Umbilical cord vasculitis: tweak) |
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*Abbreviation ''PFD''. | *Abbreviation ''PFD''. | ||
===General=== | ===General=== | ||
*Massive perivillous fibrin deposition is | *Massive perivillous fibrin deposition is associated with anti-phospholipid antibody (APLA) syndrome.<ref name=pmid12066949>{{cite journal |author=Sebire NJ, Backos M, Goldin RD, Regan L |title=Placental massive perivillous fibrin deposition associated with antiphospholipid antibody syndrome |journal=BJOG |volume=109 |issue=5 |pages=570–3 |year=2002 |month=May |pmid=12066949 |doi= |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1470-0328&date=2002&volume=109&issue=5&spage=570}}</ref> | ||
**APLA is | **APLA is associated with recurrent miscarriage - can be treated with heparin + ASA.<ref name=pmid12066949/> | ||
*Thought to be an immunologic problem - resulting in platelet activation and fibrin deposition.<ref name=pmid12066949/> | *Thought to be an immunologic problem - resulting in platelet activation and fibrin deposition.<ref name=pmid12066949/> | ||
*May be associated with [[diabetes mellitus]].<ref name=Ref_Placenta327>{{Ref Placenta|327}}</ref> | *May be associated with [[diabetes mellitus]].<ref name=Ref_Placenta327>{{Ref Placenta|327}}</ref> | ||
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Notes: | Notes: | ||
*Nuclei of villi are | *Nuclei of villi are usually preserved. | ||
*Villi may have secondary infarction, i.e. there may be [[Basics#Nuclear destruction words|nuclear destruction]] (karyolysis, karyorrhexis, pyknosis). | *Villi may have secondary infarction, i.e. there may be [[Basics#Nuclear destruction words|nuclear destruction]] (karyolysis, karyorrhexis, pyknosis). | ||
DDx: | |||
*[[Placental infarction]] - loss of nuclei in the villi (below the edge of the lesion). | |||
Images: | Images: | ||
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===Sign out=== | ===Sign out=== | ||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, BIRTH: | |||
- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. | |||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | |||
- SMALL PLACENTAL DISC WITH MASSIVE PERIVILLOUS FIBRIN DEPOSITION | |||
</pre> | |||
====Thrombi==== | ====Thrombi==== | ||
<pre> | <pre> | ||