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Difference between revisions of "Dermatologic neoplasms"
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Dermatologic neoplasms (view source)
Revision as of 12:32, 28 December 2012
, 12:32, 28 December 2012→Sebaceous carcinoma
(→Sebaceous carcinoma: +aka) |
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Features:<ref name=Ref_Derm431-2>{{Ref Derm|431-2}}</ref> | Features:<ref name=Ref_Derm431-2>{{Ref Derm|431-2}}</ref> | ||
*CK7 +ve<ref name=pmid21592202>{{Cite journal | last1 = Ansai | first1 = S. | last2 = Arase | first2 = S. | last3 = Kawana | first3 = S. | last4 = Kimura | first4 = T. | title = Immunohistochemical findings of sebaceous carcinoma and sebaceoma: retrieval of cytokeratin expression by a panel of anti-cytokeratin monoclonal antibodies. | journal = J Dermatol | volume = 38 | issue = 10 | pages = 951-8 | month = Oct | year = 2011 | doi = 10.1111/j.1346-8138.2011.01274.x | PMID = 21592202 }}</ref> - often weak. | *CK7 +ve<ref name=pmid21592202>{{Cite journal | last1 = Ansai | first1 = S. | last2 = Arase | first2 = S. | last3 = Kawana | first3 = S. | last4 = Kimura | first4 = T. | title = Immunohistochemical findings of sebaceous carcinoma and sebaceoma: retrieval of cytokeratin expression by a panel of anti-cytokeratin monoclonal antibodies. | journal = J Dermatol | volume = 38 | issue = 10 | pages = 951-8 | month = Oct | year = 2011 | doi = 10.1111/j.1346-8138.2011.01274.x | PMID = 21592202 }}</ref> - often weak. | ||
*EMA +ve. | *EMA +ve -- only sebaceous component.<ref name=pmid10369589/> | ||
*CEA -ve. | *CEA -ve. | ||
**Positive in [[ | **Positive in [[extramammary Paget disease]], sweat duct tumours. | ||
Images: | |||
*[http://archopht.jamanetwork.com/data/journals/ophth/9858/m_ecs8482f1.png Sebaceous carcinoma - EMA, AE1/AE3, CAM5.2 (jamanetwork.com)].<ref name=pmid10369589>{{Cite journal | last1 = Sinard | first1 = JH. | title = Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma. | journal = Arch Ophthalmol | volume = 117 | issue = 6 | pages = 776-83 | month = Jun | year = 1999 | doi = | PMID = 10369589 }}</ref> | |||
===Sign out=== | |||
<pre> | |||
SKIN LESION, NOSE, BIOPSY: | |||
- SEBACEOUS CARCINOMA, WELL-DIFFERENTIATED, COMPLETELY EXCISED IN THE PLANE OF SECTION. | |||
COMMENT: | |||
EMA staining marks the sebocytes. The lesion is negative for Ber-EP4. | |||
</pre> | |||
==Microcystic adnexal carcinoma== | ==Microcystic adnexal carcinoma== | ||