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Difference between revisions of "Inflammatory bowel disease"
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Inflammatory bowel disease (view source)
Revision as of 01:54, 28 December 2012
, 01:54, 28 December 2012→Specimens
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*Biopsies for diagnosis. | *Biopsies for diagnosis. | ||
*Surveillance biopsies - to rule-out dysplasia. | *Surveillance biopsies - to rule-out dysplasia. | ||
*Resections | *Resections for disease that has failed medical management. | ||
*Resections for dysplasia associated with inflammatory bowel disease. | *Resections for dysplasia associated with inflammatory bowel disease. | ||
Notes: | |||
* | *Biopsies for diagnosis should specify the (anatomical) site: | ||
**Slight gradients | **Slight gradients exist in the large bowel that can be exploited for diagnostic purposes if the site information is known, for example: | ||
***Paneth cell distal to the splenic flexure are abnormal. | ***Paneth cell distal to the splenic flexure are abnormal. | ||
***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ||
*Surveillance biopsies should specify the (anatomical) site - so, it possible to find any site of interest on a follow-up colonoscopy.<ref name=pmid16609751>{{Cite journal | last1 = Panaccione | first1 = R. | title = The approach to dysplasia surveillance in inflammatory bowel disease. | journal = Can J Gastroenterol | volume = 20 | issue = 4 | pages = 251-3 | month = Apr | year = 2006 | doi = | PMID = 16609751 | PMC = 2659899}}</ref> | |||
===Spanking the clinician for submitting it all in one bottle=== | ===Spanking the clinician for submitting it all in one bottle=== | ||