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Difference between revisions of "Malignant melanoma"
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→General: +gross
(→General: +gross) |
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===Clinical=== | ===Clinical=== | ||
Serologic predictors of a poor prognosis: | Serologic predictors of a poor prognosis: | ||
*Lactate dehydrogenase (LDH) > 200-225 U/L. | *Lactate dehydrogenase (LDH) > 200-225 U/L. | ||
| Line 29: | Line 27: | ||
*Typically Caucasians. | *Typically Caucasians. | ||
**Blacks rarely get melanoma. When they do it is often on the palms or soles.<ref>{{Ref APBR|362 Q49}}</ref><ref name=pmid17373156>{{Cite journal | last1 = Byrd-Miles | first1 = K. | last2 = Toombs | first2 = EL. | last3 = Peck | first3 = GL. | title = Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians. | journal = J Drugs Dermatol | volume = 6 | issue = 1 | pages = 10-6 | month = Jan | year = 2007 | doi = | PMID = 17373156 }}</ref> | **Blacks rarely get melanoma. When they do it is often on the palms or soles.<ref>{{Ref APBR|362 Q49}}</ref><ref name=pmid17373156>{{Cite journal | last1 = Byrd-Miles | first1 = K. | last2 = Toombs | first2 = EL. | last3 = Peck | first3 = GL. | title = Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians. | journal = J Drugs Dermatol | volume = 6 | issue = 1 | pages = 10-6 | month = Jan | year = 2007 | doi = | PMID = 17373156 }}</ref> | ||
==Gross== | |||
Memory device ''ABCDE'':<ref name=Ref_Derm466>{{Ref Derm|466}}</ref> | |||
*Asymmetric. | |||
*Borders (irregular). | |||
*Colour (black - variable in lesion). | |||
*Diameter (larger than 6 mm). | |||
*Evolving (change with time). | |||
==Microscopic== | ==Microscopic== | ||