Difference between revisions of "Malignant melanoma"

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27 bytes added ,  12:34, 18 December 2012
(→‎General: +gross)
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===Clinical===
===Clinical===
*''ABCDE'' = asymmetric, borders (irregular), colour (black - variable in lesion), diameter (larger than 6 mm), evolving (change with time).<ref name=Ref_Derm466>{{Ref Derm|466}}</ref>
Serologic predictors of a poor prognosis:
Serologic predictors of a poor prognosis:
*Lactate dehydrogenase (LDH) > 200-225 U/L.
*Lactate dehydrogenase (LDH) > 200-225 U/L.
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*Typically Caucasians.  
*Typically Caucasians.  
**Blacks rarely get melanoma. When they do it is often on the palms or soles.<ref>{{Ref APBR|362 Q49}}</ref><ref name=pmid17373156>{{Cite journal  | last1 = Byrd-Miles | first1 = K. | last2 = Toombs | first2 = EL. | last3 = Peck | first3 = GL. | title = Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians. | journal = J Drugs Dermatol | volume = 6 | issue = 1 | pages = 10-6 | month = Jan | year = 2007 | doi =  | PMID = 17373156 }}</ref>
**Blacks rarely get melanoma. When they do it is often on the palms or soles.<ref>{{Ref APBR|362 Q49}}</ref><ref name=pmid17373156>{{Cite journal  | last1 = Byrd-Miles | first1 = K. | last2 = Toombs | first2 = EL. | last3 = Peck | first3 = GL. | title = Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians. | journal = J Drugs Dermatol | volume = 6 | issue = 1 | pages = 10-6 | month = Jan | year = 2007 | doi =  | PMID = 17373156 }}</ref>
==Gross==
Memory device ''ABCDE'':<ref name=Ref_Derm466>{{Ref Derm|466}}</ref>
*Asymmetric.
*Borders (irregular).
*Colour (black - variable in lesion).
*Diameter (larger than 6 mm).
*Evolving (change with time).


==Microscopic==
==Microscopic==
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