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Difference between revisions of "Cardiac tumours"
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→Cardiac myxoma: more
m (→Microscopic) |
(→Cardiac myxoma: more) |
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Features:<ref name=pmid12006696/> | Features:<ref name=pmid12006696/> | ||
*[[myxoid stroma|Myxoid]] material - extra cellular - '''key feature'''. | *[[myxoid stroma|Myxoid]] material - extra cellular - '''key feature'''. | ||
*Myxoma cells - stellate, polygonal.<ref name=pmid16508920>{{Cite journal | last1 = Orlandi | first1 = A. | last2 = Ciucci | first2 = A. | last3 = Ferlosio | first3 = A. | last4 = Genta | first4 = R. | last5 = Spagnoli | first5 = LG. | last6 = Gabbiani | first6 = G. | title = Cardiac myxoma cells exhibit embryonic endocardial stem cell features. | journal = J Pathol | volume = 209 | issue = 2 | pages = 231-9 | month = Jun | year = 2006 | doi = 10.1002/path.1959 | PMID = 16508920 }}</ref> | |||
*Calcified elastic fibers - ''gamna bodies''. | *Calcified elastic fibers - ''gamna bodies''. | ||
*Hemorrhage common. | *Hemorrhage common. | ||
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====Micro==== | ====Micro==== | ||
The sections show paucicellular myxoid material containing spindled-to-epithelioid cells with eosinophilic myxoid cytoplasm and bland nuclei (myxoma cells). Hemosiderin-laden macrophages, calcified elastic fibres and scattered inflammatory cells are also present. There is no nuclear atypia. Mitotic activity is not evident. | The sections show paucicellular myxoid material containing spindled-to-epithelioid cells with eosinophilic myxoid cytoplasm and bland nuclei (myxoma cells). Hemosiderin-laden macrophages, calcified elastic fibres (gamna bodies) and scattered inflammatory cells are also present. There is no nuclear atypia. Mitotic activity is not evident. Several sections show fresh hemorrhage. The edge has a fibrotic rim and appears to be covered by endothelium. No cardiac muscle is identified. | ||
Several sections show fresh hemorrhage. The edge has a fibrotic rim and appears to be covered by endothelium. | |||
No cardiac muscle is identified. | |||
==Papillary fibroelastoma== | ==Papillary fibroelastoma== | ||