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*Biopsy should consist of 2-3 sites. In children it is important to sample the duodenal cap, as it is the only affected site in ~10% of cases. | *Biopsy should consist of 2-3 sites. In children it is important to sample the duodenal cap, as it is the only affected site in ~10% of cases. | ||
*Flat lesions without IELs are unlikely to be celiac sprue. | *Flat lesions without IELs are unlikely to be celiac sprue. | ||
*Mucosa erosions are rare in celiac sprue; should prompt consideration of an alternate diagnosis (infection, medications, Crohn's disease). | |||
===Grading=== | ===Grading=== |
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