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Difference between revisions of "Stomach"
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→Intestinal metaplasia of the stomach
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Goblet cells are present in the stomach.<ref>URL: [http://esynopsis.uchc.edu/eAtlas/GI/1280.htm http://esynopsis.uchc.edu/eAtlas/GI/1280.htm]. Accessed on: 16 August 2010.</ref> | *Goblet cells are present in the stomach - '''key feature'''.<ref>URL: [http://esynopsis.uchc.edu/eAtlas/GI/1280.htm http://esynopsis.uchc.edu/eAtlas/GI/1280.htm]. Accessed on: 16 August 2010.</ref> | ||
**In [[H&E stain|H&E]] the vacuole often stains light grey. | **In [[H&E stain|H&E]] the vacuole often stains light grey. | ||
*Paneth cells are present - deep in the glands.<ref name=pmid19918317/> | |||
**Very rarely present. | |||
**Very uncommon in isolation. | |||
Image: | Image: | ||
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}}</ref> | }}</ref> | ||
**Strong assoc. with ''[[Helicobacter gastritis]]'' as well as IM.<ref name=pmid12047325>{{Cite journal | last1 = Satoh | first1 = K. | last2 = Mutoh | first2 = H. | last3 = Eda | first3 = A. | last4 = Yanaka | first4 = I. | last5 = Osawa | first5 = H. | last6 = Honda | first6 = S. | last7 = Kawata | first7 = H. | last8 = Kihira | first8 = K. | last9 = Sugano | first9 = K. | title = Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. | journal = Helicobacter | volume = 7 | issue = 3 | pages = 192-8 | month = Jun | year = 2002 | doi = | PMID = 12047325 }}</ref> | **Strong assoc. with ''[[Helicobacter gastritis]]'' as well as IM.<ref name=pmid12047325>{{Cite journal | last1 = Satoh | first1 = K. | last2 = Mutoh | first2 = H. | last3 = Eda | first3 = A. | last4 = Yanaka | first4 = I. | last5 = Osawa | first5 = H. | last6 = Honda | first6 = S. | last7 = Kawata | first7 = H. | last8 = Kihira | first8 = K. | last9 = Sugano | first9 = K. | title = Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. | journal = Helicobacter | volume = 7 | issue = 3 | pages = 192-8 | month = Jun | year = 2002 | doi = | PMID = 12047325 }}</ref> | ||
Others: | |||
*Lysozyme +ve - marks paneth cells.<ref name=pmid19918317>{{Cite journal | last1 = Rubio | first1 = CA. | last2 = Befrits | first2 = R. | title = Increased lysozyme expression in gastric biopsies with intestinal metaplasia and pseudopyloric metaplasia. | journal = Int J Clin Exp Med | volume = 2 | issue = 3 | pages = 248-53 | month = | year = 2009 | doi = | PMID = 19918317 }}</ref> | |||
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