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==Pancreatic acinar metaplasia== | ==Pancreatic acinar metaplasia== | ||
*[[AKA]] pancreatic metaplasia. | *Abbreviated ''PAM''. | ||
*[[AKA]] ''pancreatic metaplasia''.<ref name=pmid8724024>{{Cite journal | last1 = Stachura | first1 = J. | last2 = Konturek | first2 = JW. | last3 = Urbanczyk | first3 = K. | last4 = Bogdal | first4 = J. | last5 = Mach | first5 = T. | last6 = Domschke | first6 = W. | title = Endoscopic and histological appearance of pancreatic metaplasia in the human gastric mucosa: a preliminary report on a recently recognized new type of gastric mucosal metaplasia. | journal = Eur J Gastroenterol Hepatol | volume = 8 | issue = 3 | pages = 239-43 | month = Mar | year = 1996 | doi = | PMID = 8724024 }}</ref> | |||
===General=== | ===General=== | ||
*Common in the GI tract. | *Common in the GI tract. | ||
*Found in ~ 20% of [[eosphageal]] biopsies above the GEJ.<ref name=pmid20012917>{{cite journal |author=Johansson J, Håkansson HO, Mellblom L, ''et al.'' |title=Pancreatic acinar metaplasia in the distal oesophagus and the gastric cardia: prevalence, predictors and relation to GORD |journal=J. Gastroenterol. |volume=45 |issue=3 |pages=291–9 |year=2010 |month=March |pmid=20012917 |doi=10.1007/s00535-009-0161-4 |url=}}</ref> | *Found in ~ 20% of [[eosphageal]] biopsies above the GEJ.<ref name=pmid20012917>{{cite journal |author=Johansson J, Håkansson HO, Mellblom L, ''et al.'' |title=Pancreatic acinar metaplasia in the distal oesophagus and the gastric cardia: prevalence, predictors and relation to GORD |journal=J. Gastroenterol. |volume=45 |issue=3 |pages=291–9 |year=2010 |month=March |pmid=20012917 |doi=10.1007/s00535-009-0161-4 |url=}}</ref> | ||
===Gross=== | |||
*May be a single lesion or a cluster of lesions.<ref name=pmid8724024/> | |||
===Microscopic=== | ===Microscopic=== | ||
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*[http://commons.wikimedia.org/w/index.php?title=File:Pancreatic_acinar_metaplasia_-_high_mag.jpg PAM - high mag. (WC)]. | *[http://commons.wikimedia.org/w/index.php?title=File:Pancreatic_acinar_metaplasia_-_high_mag.jpg PAM - high mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Pancreatic_acinar_metaplasia_-_low_mag.jpg PAM - low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Pancreatic_acinar_metaplasia_-_low_mag.jpg PAM - low mag. (WC)]. | ||
===IHC=== | |||
Features:<ref>{{Cite journal | last1 = Doglioni | first1 = C. | last2 = Laurino | first2 = L. | last3 = Dei Tos | first3 = AP. | last4 = De Boni | first4 = M. | last5 = Franzin | first5 = G. | last6 = Braidotti | first6 = P. | last7 = Viale | first7 = G. | title = Pancreatic (acinar) metaplasia of the gastric mucosa. Histology, ultrastructure, immunocytochemistry, and clinicopathologic correlations of 101 cases. | journal = Am J Surg Pathol | volume = 17 | issue = 11 | pages = 1134-43 | month = Nov | year = 1993 | doi = | PMID = 8214258 }}</ref> | |||
*Trypase +ve. | |||
*Lipase +ve. | |||
==Pancreatic ectopia== | ==Pancreatic ectopia== |
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